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Table 1 Baseline characteristics of the subjects (n = 362)

From: Severe fever with thrombocytopenia syndrome: comparison with scrub typhus and clinical diagnostic prediction

Variable

Scrub typhus (n = 255)

SFTS

P valuec

Eschar-positive

P valuea

Eschar-negative

P valueb

n = 205

n = 50

n = 107

Age, years (median, IQR)

60 (49–71)

< 0.001

64.5 (51.2–70.7)

0.004

71 (61–78)

< 0.001

Male gender, n (%)

81 (39.5)

0.044

22 (44.0)

0.387

55 (51.4)

0.054

Comorbidity

 Diabetes mellitus

19 (9.3)

0.027

5 (10.0)

0.200

19/106 (17.9)

0.023

 Hypertension

44 (21.5)

0.030

13 (26.0)

0.395

35 (32.7)

0.039

 CVA

7 (3.4)

1.000

1 (2.0)

1.000

4 (3.7)

0.771

 Congestive heart failure

9 (4.4)

0.342

2 (4.0)

0.593

2 (1.9)

0.254

 Chronic liver disease

7 (3.4)

0.272

5 (10.0)

0.013

1 (0.9)

0.119

 Asthma/COPD

7 (3.4)

0.583

1 (2.0)

0.665

5 (4.7)

0.474

 Solid tumor

6 (2.9)

0.098

2 (4.0)

0.098

0

0.111

 None

126 (61.5)

0.121

26 (52.0)

0.969

56 (52.3)

0.202

Seasonal occurrence, n (%)

 Spring-summer (Mar-Aug)

0

< 0.001

0

< 0.001

67 (62.6)

< 0.001

 Autumn (Sep-Dec)

205 (100)

 

50 (100)

 

40 (37.4)

 

Geographical location

 Western area

167 (81.5)

< 0.001

42 (84.0)

< 0.001

36/104 (34.6)

< 0.001

 Eastern area

38 (18.5)

 

8 (16.0)

 

68/104 (65.4)

 

Duration, mean (±SD), days

 From onset of illness to admission

6.63 (3.918)

< 0.001

6.38 (5.103)

0.006

4.39 (3.66))

< 0.001

 Hospital stay

6.26 (11.927)

< 0.001

6.18 (3.757)

< 0.001

12.07 (9.57)

< 0.001

Mortality, in-hospital

1 (0.5)

< 0.001

0

< 0.001

43 (40.2)

< 0.001

  1. Abbreviations: SFTS severe fever with thrombocytopenia syndrome, IQR interquartile range, SD standard deviation, CVA cerebrovascular accident, COPD chronic obstructive lung disease
  2. aP value when compared to SFTS
  3. bP value when compared to SFTS
  4. cP value when compared to all scrub typhus