Severe fever with thrombocytopenia syndrome: comparison with scrub typhus and clinical diagnostic prediction

BMC Infectious Diseases

Table 4 Major complications during the clinical course (n = 362)

Variable	Scrub typhus (n = 255)				SFTS	P value^c
	Eschar-positive	P value^a	Eschar-negative	P value^b	n = 107
	n = 205	P value^a	n = 50	P value^b	n = 107
CNS involvement
Altered mentality (GCS < 15)	14/199 (7.0)	< 0.001	8 (16.0)	< 0.001	62/105 (59.0)	< 0.001
Seizure	0/199 (0)	< 0.001	0 (0)	0.002	17/105 (16.2)	< 0.001
Lung involvement
Mechanical ventilation	5 (2.4)	< 0.001	2 (4.0)	< 0.001	34/106 (32.1)	< 0.001
Renal involvement
Acute kidney injury	5 (2.4)	< 0.001	5 (10.0)	0.080	23 (21.5)	< 0.001

Abbreviations: SFTS severe fever with thrombocytopenia syndrome, CNS central nervous system, GCS Glasgow coma scale
^aP value when compared to SFTS
^bP value when compared to SFTS
^cP value when compared to all scrub typhus

ISSN: 1471-2334