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Table 2 Distribution of signs meeting SIRS criteria in patients with sepsis or septic shock*

From: Systemic inflammatory response syndrome in Sepsis-3: a retrospective study

Variable

All Patients (n = 631)

Patients with SIRS-Positive Severe Sepsis (n = 538)

Patients with SIRS-Negative Severe Sepsis (n = 93)

SIRS criterion met — no. (%)a

 Abnormal temperature

630 (99.8)

250 (46.5)

6 (6.5)

 Increased heart rate

631 (100)

506 (94.1)

43 (46.2)

 Increased respiratory rate or decreased PaCO2

630 (99.8)

448 (83.3)

15 (16.1)

 Abnormal white-cell count

629 (99.7)

331 (61.6)

13 (14.1)

No. of SIRS criteria met

 Median

3

3

1

 Interquartile range

2–3

2–3

1–1

 Distribution

  > 1

538 (85.3)

538 (85.3)

0

  0

16 (2.5)

 

16 (17.2)

  1

77 (12.2)

 

77 (82.8)

  2

200 (31.7)

200 (37.2)

0

  3

218 (34.5)

218 (40.5)

0

  4

120 (19.0)

120 (22.3)

0

  1. * P < 0.001 for all comparisons between the SIRS-positive group and the SIRS-negative group. PaCO2 denotes partial pressure of arterial carbon dioxide
  2. a SIRS criteria are defined in the Supplementary Appendix. Patients may have more than one criterion