From: Use of Ceftaroline Fosamil in Osteomyelitis: CAPTURE Study Experience
Category, n (%) | CAPTURE N = 150 |
---|---|
Mean (±SD) duration of dosing, d | 8.0 (±7.2) |
Median (range) duration of dosing, d | 6.0 (2–45) |
CPT-F dose per treatmenta | |
200 mg | 11 (7.3) |
300 mg | 10 (6.7) |
400 mg | 23 (15.3) |
600 mg | 117 (78.0) |
CPT-F frequencya | |
Every 6 h | 0 |
Every 8 h | 10 (6.7) |
Every 12 h | 143 (95.3) |
Every 24 h | 1 (0.7) |
CPT-F used as monotherapy | 100 (66.7) |
CPT-F used as concurrent therapy | 50 (33.3) |
Prior antibiotics administereda | |
Vancomycin | 81 (54.0) |
Piperacillin with tazobactam | 28 (18.7) |
Daptomycin | 26 (17.3) |
Concurrent antibiotics administeredab | |
Metronidazole | 18 (12.0) |
Vancomycin | 8 (5.3) |
Daptomycin | 7 (4.7) |
Subsequent antibiotics administeredab | |
CPT-F | 35 (23.3) |
Daptomycin | 14 (9.3) |
Vancomycin | 14 (9.3) |