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Table 2 Predictors of late (> 3 months of age) or no receipt of DTP1 vaccination among urban Dar es Salaam (n = 11,189) and rural Morogoro (n = 19,767) infants

From: Determinants of delayed or incomplete diphtheria-tetanus-pertussis vaccination in parallel urban and rural birth cohorts of 30,956 infants in Tanzania

Characteristic

Urban Dar es Salaam

Rural Morogoro Region

p-value for interaction by site

Total N

Late or no receipt of DTP1

n (%)

Multivariate Relative Risk (95% CI)

p value

Total N

Late or no receipt of DTP1

n (%)

Multivariate Relative Risk (95% CI)

p value

Total cohort

11,189

1283 (11.47%)

–

–

19,767

1808 (9.15%)

–

–

 

Infant sex

 Male

5712

669 (11.71%)

1.04 (0.94–1.16)

0.40

10,517

983 (9.35%)

1.05 (0.96–1.15)

0.26

0.93

 Female

5473

613 (11.20%)

Reference

 

9250

826 (8.93%)

Reference

  

Parity

 Firstborn

2577

332 (12.88%)

Reference

 

4865

514 (10.57%)

Reference

 

0.17

 2nd-4th child

5239

566 (10.80%)

0.95 (0.82–1.10)

0.48

9083

808 (8.90%)

0.83 (0.73–0.94)

0.003

 

 5th or greater child

686

80 (11.66%)

1.05 (0.81–1.35)

0.73

3006

330 (10.98%)

1.05 (0.89–1.25)

0.53

 

Birthweight

 Low birthweight (< 2500 g)

967

113 (11.69%)

0.95 (0.79–1.14)

0.56

2741

184 (6.71%)

0.69 (0.60–0.80)

<  0.001

0.009

 Normal birthweight (≥2500 g)

10,208

1167 (11.43%)

Reference

 

17,026

1625 (9.54%)

Reference

  

Gestational Age

 Preterm (< 37 weeks)

1511

172 (11.38%)

1.00 (0.85–1.17)

0.97

1887

189 (10.02%)

0.99 (0.85–1.16)

0.91

0.60

 Term (≥37 weeks)

6430

674 (10.48%)

Reference

 

9978

898 (9.00%)

Reference

  

Size for gestational Age

 SGA (<10th percentile)

729

77 (10.56%)

0.88 (0.71–1.11)

0.28

1572

134 (8.52%)

0.93 (0.78–1.11)

0.40

0.76

 No SGA (≥10th percentile)

7084

755 (10.66%)

Reference

 

9987

918 (9.19%)

Reference

  

Maternal age

  < 20 years

1835

247 (13.46%)

1.48 (1.23–1.78)

<  0.001*

4517

446 (9.87%)

1.00 (0.86–1.15)

0.003*

0.23

 20–25 years

3269

340 (10.40%)

1.18 (1.01–1.39)

 

5266

513 (9.74%)

1.08 (0.96–1.22)

  

 25–30 years

2825

247 (8.74%)

Reference

 

5256

478 (9.09%)

Reference

  

 30–35 years

1396

121 (8.67%)

0.96 (0.78–1.18)

 

2744

208 (7.58%)

0.82 (0.70–0.96)

  

  ≥ 35 years

589

54 (9.17%)

0.98 (0.73–1.31)

 

1397

107 (7.66%)

0.77 (0.62–0.94)

  

Maternal education

 No formal schooling

466

58 (12.45%)

1.16 (0.90–1.50)

0.05*

2098

264 (12.58%)

1.13 (0.98–1.30)

0.17*

0.29

 Some primary

347

43 (12.39%)

1.09 (0.82–1.45)

 

1872

203 (10.84%)

1.10 (0.95–1.28)

  

 Completed primary

7291

746 (10.23%)

Reference

 

13,974

1169 (8.37%)

Reference

  

 Secondary plus

1656

144 (8.70%)

0.89 (0.74–1.06)

 

1225

107 (8.73%)

1.11 (0.91–1.35)

  

Paternal education

 No formal schooling

189

20 (10.58%)

0.88 (0.58–1.35)

0.14*

1218

197 (16.17%)

1.59 (1.36–1.87)

<  0.001*

0.04

 Some primary

221

38 (17.19%)

1.57 (1.16–2.11)

 

1481

177 (11.95%)

1.32 (1.13–1.53)

  

 Completed primary

6631

686 (10.35%)

Reference

 

14,588

1228 (8.42%)

Reference

  

 Secondary plus

2742

243 (8.86%)

0.93 (0.80–1.08)

 

1889

139 (7.36%)

0.93 (0.78–1.11)

  

Wealth quintile

 Q1 (Poorest)

1577

208 (13.12%)

1.43 (1.13–1.80)

0.01*

3988

433 (10.86%)

1.32 (1.13–1.54)

<  0.001*

0.02

 Q2

2325

232 (9.98%)

1.12 (0.89–1.41)

 

4350

488 (11.22%)

1.35 (1.16–1.57)

  

 Q3

1712

183 (10.69%)

1.24 (0.98–1.57)

 

3247

240 (7.39%)

1.04 (0.88–1.23)

  

 Q4

2988

283 (9.47%)

1.15 (0.92–1.42)

 

3810

318 (8.35%)

1.13 (0.97–1.32)

  

 Q5 (Richest)

1282

102 (7.96%)

Reference

 

3828

276 (7.21%)

Reference

  

Place of birtha

 Home

–

–

–

–

2646

310 (11.72%)

1.20 (1.06–1.35)

0.004

 

 Facility

–

–

–

 

17,100

1492 (8.73%)

Reference

  

Trimester of first ANC visit

 1st Trimester

1133

112 (9.89%)

0.86 (0.71–1.04)

<  0.001*

1536

144 (9.38%)

0.90 (0.76–1.06)

0.63*

0.001

 2nd Trimester

6604

737 (11.16%)

Reference

 

12,486

1259 (10.08%)

Reference

  

 3rd Trimester

802

139 (17.33%)

1.55 (1.32–1.83)

 

2031

196 (9.65%)

0.95 (0.83–1.10)

  
  1. *p value for trend
  2. aParticipants in Dar es Salaam primarily enrolled from facilities