Grading category | Definition |
---|---|
1 | Based upon high-level evidence with multiple well-designed, controlled, randomized blinded studies and meta-analysis. There is uniform consensus that the intervention is adequate. |
2A | Based upon lower level of well-controlled, non- blinded or randomized studies, with retrospective reviews. There is uniform consensus that the intervention is adequate. |
2B | Based upon lower level of well-controlled, non- blinded or randomized studies, with retrospective reviews. There is majority consensus that the intervention is adequate. |
3A | Based upon any evidence that is less than well-controlled, or randomized, or large sample studies, mostly retrospective. There is uniform consensus that the intervention is adequate. |
3B | Based upon any evidence that is less than well-controlled, or randomized, or large sample studies, mostly retrospective. There is no uniform consensus that the intervention is adequate. |
3C | Based upon any evidence that is less than well-controlled, or randomized, or large sample studies, mostly retrospective. There is no consensus that the intervention is adequate. |
4A | There is any level of evidence from literature against the intervention. There is uniform consensus against the intervention. |