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Table 5 The MICs of fluoroquinolones and gyrase mutations for 9 isolates with moxifloxacin resistance

From: Epidemiology of Clostridium difficile infection in hospitalized adults and the first isolation of C. difficile PCR ribotype 027 in central China

Number of strains

MIC (ug/ml)

Gyrase mutations

Ciprofloxacin

Levofloxacin

Moxifloxacin

GyrA

GyrB

TCD10

0.125

128

16

Thr82Ile

 

TCD17

> 128

> 128

32

Thr82Ile

 

TCD 27

64

> 128

8

Thr82Ile

 

TCD 28

32

16

16

Thr82Ile

 

TCD 42

128

> 128

32

Thr82Ile

 

TCD 53

8

16

8

Thr82Ile

 

TCD 54

64

64

32

Thr82Ile

 

TCD 58

128

> 128

32

Thr82Ile

Ser366Ala

TCD 59

64

64

32

Thr82Ile

 
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BMC Infectious Diseases

ISSN: 1471-2334

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