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Table 3 Comparison of the PM-TAC assay versus the CSF culture method

From: Development of a TaqMan Array card to target 21 purulent meningitis-related pathogens

Patients No.

CSF culture result

PM-TAC assay result

Concordance

PCR/sequencing result

Before antibiotic therapies

After antibiotic therapies

After antibiotic therapies

001

Streptococcus pneumoniae

Negative

Negative

Yes

Negative

002

Streptococcus pneumoniae

Negative

Streptococcus pneumoniae

No

Streptococcus pneumoniae

003

Klebsiella pneumoniae

Klebsiella pneumoniae

Klebsiella pneumoniae

Yes

–

004

Haemophilus influenzae

Negative

Negative

Yes

Negative

005

Klebsiella pneumoniae

Negative

Klebsiella pneumoniae

No

Klebsiella pneumoniae

006

Escherichia coli

Negative

Escherichia coli

No

Escherichia coli

007

Salmonella spp

Negative

Negative

Yes

Negative

008

Baumanii

Baumanii

Baumanii

Yes

–

009

Streptococcus pneumoniae

Negative

Negative

Yes

Negative

010

Streptococcus pneumoniae

Negative

Negative

Yes

Negative

011

Streptococcus pneumoniae

Negative

Streptococcus pneumoniae

No

Streptococcus pneumoniae

012

Escherichia coli

Negative

Escherichia coli

No

Escherichia coli

013

Escherichia coli

Negative

Escherichia coli

No

Escherichia coli

014

Streptococcus pneumoniae

Negative

Negative

Yes

Negative

015

Listeria monocytogenes

Negative

Negative

Yes

Negative