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Table 3 Univariate and Multiple Logistic Regression Risk Analyses of the Presence of Multiple Beta-lactam Non-Susceptible Isolates* by Explanatory Variables

From: An alarmingly high nasal carriage rate of Streptococcus pneumoniae serotype 19F non-susceptible to multiple beta-lactam antimicrobials among Vietnamese children

Variables

Multiple beta-lactam non-susceptible isolates (n = 40)

Other pneumococcal isolates (n = 234)

Subtotal

Odds ratio (95% CI) (univariate)

P

Odds ratio (95% CI) (multiple)

P

Gender

 Male

22 (14.2%)

133 (85.8%)

155 (100%)

Reference

   

 Female

18 (15.1%)

101 (84.9%)

119 (100%)

1.08 (0.55–2.11)

0.8285

  

Age group

 6–11 m

11 (15.3%)

61 (84.7%)

72 (100%)

Reference

   

 1–2 yr

26 (15.5%)

142 (84.5%)

168 (100%)

1.02 (0.47–2.18)

0.9689

  

  ≥ 3 yr

3 (8.8%)

31 (91.2%)

34 (100%)

0.54 (0.14–2.07)

0.3596

  

Daycare attendance

 Yes

29 (19.2%)

122 (80.8%)

151 (100%)

2.42 (1.15–5.07)

0.0167

2.56 (1.22–5.73)

0.0123

 No

11 (8.9%)

112 (91.1%)

123 (100%)

Reference

   

Situation

 ARI

18 (9.9%)

164 (90.1%)

182 (100%)

0.35 (0.18–0.69)

0.0019

0.48 (0.20–1.08)

0.0764

 Healthy children

22 (23.9%)

70 (76.1%)

92 (100%)

Reference

   

Living in a large family (≥ 5 persons)

 Yes

26 (17.7%)

121 (82.3%)

147 (100%)

1.73 (0.86–3.49)

0.1193

1.72 (0.84–3.65)

0.1423

 No

14 (11.0%)

113 (88.9%)

127 (100%)

Reference

   

Prior antibiotic use

 Yes

8 (8.3%)

89 (91.8%)

97 (100%)

0.41 (0.18–0.92)

0.0275

0.65 (0.23–1.76)

0.3975

 No or unknown

32 (18.1%)

145 (81.9%)

177 (100%)

Reference

   
  1. This analysis was performed for cases with pneumococcal isolates that contained a single serotype (n = 274) after exclusion of ARI cases in children < 6 m
  2. *PEN MIC ≥4 μg/mL, CTX MIC ≥2 μg/mL and MEM MIC ≥0.5 μg/mL