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Table 1 Demographic and clinical characteristics of patients enrolled for severe respiratory and influenza-like illness surveillance and asymptomatic controls, South Africa, June 2012 – May 2016 (N = 12,922)

From: Challenges and clinical relevance of molecular detection of Bordetella pertussis in South Africa

Characteristic

Surveillance population

SRI n/N (%) N = 5634

ILI n/N (%) N = 4933

Controls n/N (%) N = 2355

Gender

 Male

2861/5626 (51)

1757/4733 (37)

774/2291 (34)

 Female

2765/5626 (49)

2976/4733 (63)

1517/2291 (66)

Race

 Black

5473/5604 (98)

4723/4728 (100)

2287/2292 (100)

 Non-black

131/5604 (2)

5/4728 (0)

5/2292 (0)

Age group (years)

  < 1

1307/5618 (23)

599/4921 (12)

323/2352 (14)

 1–4

764/5618 (14)

1019/4921 (21)

464/2352 (20)

 5–14

168/5618 (3)

727/4921 (15)

520/2352 (22)

 15–24

276/5618 (5)

649/4921 (13)

191/2352 (8)

 25–44

1756/5618 (31)

1388/4921 (28)

371/2352 (16)

 45–64

1051/5618 (19)

460/4921 (9)

337/2352 (14)

  ≥ 65

296/5618 (5)

79/4921 (2)

146/2352 (6)

Underlying illness*

 No

5023/5627 (89)

4484/4723 (95)

2172/2290 (95)

 Yes

604/5627 (11)

239/4723 (5)

118/2290 (5)

HIV status

 Uninfected

2577/5308 (49)

3253/4451 (73)

1314/2263 (58)

 Infected

2731/5308 (51)

1198/4451 (27)

949/2263 (42)

Hospital/Clinic

 Edendale

2507/5634 (45)

N/A

N/A

 KTHC

3127/5634 (56)

N/A

N/A

 Edendale Gateway

N/A

3655/4933 (74)

1041/2355 (44)

 Jouberton Clinic

N/A

1278/4933 (26)

1314/2355 (56)

  1. SRI = Severe respiratory illness; ILI = Influenza-like illness; N/A = Not applicable; KTHC = Klerksdorp Tshepong hospital complex
  2. *Patients with previously diagnosed chronic conditions including asthma, chronic lung diseases, cirrhosis/liver failure, chronic renal failure, heart failure, valvular heart disease, coronary heart disease, immunosuppressive therapy, splenectomy, diabetes, burns, kwashiorkor/marasmus, nephrotic syndrome, spinal cord injury, seizure disorder, emphysema, or cancer. All percentages are rounded off