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Table 1 Differences in characteristics between fibrocavitary and nodular bronchiectatic types (N = 27)

From: Multiplex cytokine analysis in Mycobacterium avium complex lung disease: relationship between CXCL10 and poor prognostic factors

Characteristics Radiographic Features *P-value
FC NB
Number (%) 6 (22) 21 (78)  
Age (y) 75 (61–78) 71 (64–78) NS
Men (%) 2 (33) 3 (14) NS
BMI (kg/m2) 16.5 ± 2.7 19.5 ± 2.5 < 0.05
Anemia (%) 3 (50) 7 (33) NS
Iron deficiency (%) 2 (33) 3 (14) NS
Undernutrition (%) 5 (83) 8 (38) NS
With immunosuppressive drug (%) 0 (0) 7 (29) NS
Untreated at baseline (%) 1 (17) 14 (67) NS
Causative organism (%)
Mycobacterium. avium 5 (83) 16 (76)  
Mycobacterium. intracellulare 1 (17) 3 (14)  
M. avium and M. intracellulare 0 (0) 2 (10)  
Lymphocytes (/μL) 1095 ± 307 1329 ± 417 NS
Red blood cells (× 104/μL) 422 ± 39 418 ± 52 NS
Hb (g/dL) 12.5 ± 1.2 12.7 ± 1.5 NS
Albumin (g/dL) 3.1 (3.0–3.9) 4.0 (3.7–4.1) < 0.01
Pre-albumin (mg/dL) 14.7 ± 10.0 21.9 ± 3.9 NS
Fe (μg/dL) 49 (19–105) 84 (49–109) NS
UIBC (μg/dL) 192 ± 34 184 ± 70 NS
TIBC (μg/dL) 251 ± 37 265 ± 64 NS
TSAT (%) 22.6 ± 14.8 32.3 ± 17.2 NS
Ferritin (ng/mL) 74 (23–159) 48 (19–107) NS
CRP (mg/dL) 4.6 (0.2–6.9) 0.1 (0.1–1.2) < 0.05
SAA (mg/dL) 241.5 (6.3–726.2) 3.7 (2.4–28.7) NS
ESR (mm/hr) 70 (31–96) 19 (750) < 0.05
Anti-GPL core antibody positive (%) 5 (83) 11 (52) NS
HRCT scores 25 (12–31) 9 (6–15) < 0.05
  1. Data are presented as number (%), mean ± standard deviation, or median (interquartile range)
  2. Abbreviations, FC fibrocavitary type, NB nodular bronchiectatic type, BMI body mass index, Hb hemoglobin, UIBC unsaturated iron binding capacity, TIBC total iron binding capacity, TSAT transferrin saturation, CRP C-reactive protein, SAA serum amyloid A, ESR erythrocyte sedimentation rate, GPL glycopeptidolipid, HRCT high-resolution computed tomography
  3. Definitions: Anemia: Hb < 12 g/dL in men, < 11 g/dL in women; Iron deficiency: TSAT < 20% and ferritin < 80 μg/mL; Undernutrition: albumin < 3 .5g/dL or pre-albumin < 22 mg/dL; Anti-GPL-core antibody-positive: > 0.7 U/mL
  4. *P-values were calculated in relation to two radiographic features. Fisher’s exact test was used for categorical variables, and Student’s t-test or the Wilcoxon rank sum test for continuous variables. Welch’s t-test was used for pre-albumin. NS, not significant