Table 4 Correlations between volume of prescribed penicillins and clarithromycin and/or clindamycin and resistance rates (%) in all practices, adult and paediatric practices

 Prescription of

S. pneumoniae resistance to

rho

p-value

 Penicillins (J01C)

Penicillin

0.39

0.084

 Macrolides, lincosamides (J01F)

Clarithromycin and/or clindamycin

0.76

0.001

 Prescription of

S. pneumoniae resistance to

rho

p-value

 Penicillins (J01C)

Penicillin

0.30

0.319

 Macrolides, lincosamides (J01F)

Clarithromycin and/or clindamycin

0.63

0.021

 Prescription of

S. pneumoniae resistance to

rho

p-value

 Penicillins (J01C)

Penicillin

0.10

0.872

 Macrolides, lincosamides (J01F)

Clarithromycin and/or clindamycin

0.52

0.191