Table 4 Risk of composite adverse outcome among syphilis-seropositive pregnant women with different non-treponemal serum test titers by syphilis treatment status in Guangzhou, China, 2014–2016 ^a

  Penicillin < 28w

95 (10.6)

reference

reference

  Penicillin ≥28w

25 (34.6)

0.88 (0.59–1.33)

0.91 (0.60–1.38)^b

  No treatment

63 (41.7)

1.73 (1.31–2.28)

1.77 (1.31–2.40)^b

  2 courses

67 (14.9)

reference

reference

  1 course

31 (16.2)

1.09 (0.74–1.61)

1.21 (0.82–1.81)^c

  Insufficient treatment

22 (16.9)

1.14 (0.73–1.77)

1.22 (0.78–1.91)^c

  No treatment

63 (27.6)

1.86 (1.37–2.52)

–

  Penicillin <28w

14 (15.9)

reference

reference

  Penicillin ≥28w

10 (43.5)

2.73 (1.40–5.34)

2.34 (1.22–4.48)^b

  No treatment

34 (57.6)

3.62 (2.14–6.14)

2.93 (1.66–5.17)^b

  2 courses

6 (14.7)

reference

reference

  1 course

7 (31.3)

3.39 (1.28–9.02)

2.19 (0.90–5.31)^c

  Insufficient treatment

11 (50.0)

4.69 (1.95–11.32)

2.40 (1.05–5.52)^c

  No treatment

34 (63.4)

6.15 (2.78–13.58)

–