Clinical and microbiological characteristics of non-tuberculous mycobacteria diseases in Singapore with a focus on pulmonary disease, 2012-2016

Table 5 Comparison between male and female patients with NTM lung disease (N = 352)

Characteristics	Male (N = 182)	Female (N = 170)	P value
Median Age (25 th-75th IQR) (years)	68.5 (61–76)	66 (56–73)	0.014*
Median BMI (25th–75th IQR)	18.9 (16.2–22.3)	18.6 (16.1–21.3)	0.711
Coexisting illnesses No. (%)
HIV	11 (6.0)	2 (1.2)	0.021*
Ischemia heart disease	34 (18.7)	8 (4.7)	< 0.001*
Neoplastic disease	48 (26.4)	48 (28.2)	0.7
Diabetes mellitus	29 (15.9)	14 (8.2)	0.028*
COPD	43 (23.6)	3 (1.8)	< 0.001*
Bronchiectasis	43 (23.6)	85 (50.0)	< 0.001*
TB history	64 (35.2)	33 (19.7)	0.001*
Clinical symptoms
Cough	141 (77.5)	120 (70.6)	0.14
Recurrent cough with phlegm	94 (51.6)	66 (38.8)	0.035*
Haemoptysis	50 (27.5)	64 (37.6)	0.042*
Weight loss	38 (20.9)	33 (19.4)	0.73
Chest pain	17 (9.3)	11(6.5)	0.33
Investigations
Median albumin (25th–75th IQR)	32 (27–37.2)	34 (28–40)	0.076

Note: the data was presented as number (%) otherwise specified. Univariate analysis was performed to assess the difference in observed variables between male and female patients with NTM diseases. Categorical variables were tested by Chi-square test or Fisher’s exact test if the frequencies were less than 5*. Continuous variables were examined using non-parametric Mann-Whitney test
BMI body mass index,COPD chronic pulmonary obstructive disease,TB tuberculosis,HIV human immunodeficiency virus

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