Table 1 Patients’ characteristics at the time of HIV diagnosis according to the estimated date of infection (pre-PrEP area versus PrEP area)
Description N (%) or Median [IQR] | Pre-PrEP area infections N = 741 | PrEP area infections N = 225 | Total N = 966 | p |
|---|---|---|---|---|
Socio-demographic characteristics | ||||
Age (years) | 37 [29–47] | 33 [26–44] | 36 [29–46] | 0.001 |
Sex | ||||
Male | 507 (68.42) | 202 (89.78) | 709 (73.40) | <.0001 |
Female | 234 (31.58) | 23 (10.22) | 257 (26.60) | |
Birth area | ||||
West or central Africa | 213 (34.98) | 20 (11.30) | 233 (29.64) | <.0001 |
France | 238 (39.08) | 128 (72.32) | 366 (46.56) | |
Other | 158 (25.94) | 29 (13.37) | 187 (23.79) | |
HIV transmission route | ||||
MSM | 281 (37.97) | 168 (76.02) | 449 (46.72) | <.0001 |
Heterosexual | 365 (49.32) | 45 (20.36) | 410 (42.66) | |
Other | 94 (12.70) | 8 (3.62) | 102 (10.61) | |
CDC Stage | ||||
A | 490 (78.03) | 194 (96.04) | 684 (82.41) | <.0001 |
B | 37 (5.89) | 7 (3.47) | 44 (5.30) | |
C | 101 (16.08) | 1 (0.50) | 102 (12.29) | |
Biological data at HIV-diagnosis | ||||
HIV viral load (log cp/ml) | 4.92 [4.05–5.60] | 5.50 [4.45–6.40] | 5.20 [4.30–6.00] | <.0001 |
CD4 (cell count/mm3) | 347 [155–520] | 480 [334–635] | 378 [202–555] | <.0001 |
CD4 (cell count /mm3) | ||||
≤200 | 205 (30.73) | 14 (6.60) | 219 (24.91) | <.0001 |
200–350 | 135 (20.24) | 46 (21.70) | 181 (20.59) | |
350–500 | 145 (21.74) | 59 (27.83) | 204 (23.21) | |
>500 | 182 (27.29) | 93 (43.87) | 275 (31.29) | |
HCV antibodies | ||||
Negative | 565 (96.42) | 189 (97.93) | 754 (96.79) | 0.30 |
Positive | 21 (3.58) | 4 (2.07) | 25 (3.21) | |
HBV AgHbs | ||||
Negative | 570 (95.80) | 195 (98.98) | 765 (96.59) | 0.03 |
Positive | 25 (4.20) | 2 (1.02) | 27 (3.41) | |
HVA antibodies | ||||
Negative | 179 (37.45) | 105 (63.25) | 284 (44.10) | <.0001 |
Positive | 299 (62.55) | 61 (36.75) | 360 (55.90) | |
Syphilis serology | ||||
Negative | 340 (79.63) | 98 (65.33) | 438 (75.91) | 0.0004 |
Positive | 87 (20.37) | 52 (34.67) | 139 (24.09) | |
History of other sexuality transmitted disease (STI): N = 348 | ||||
Syphilis | ||||
No | 177 (91.24) | 110 (71.43) | 287 (82.47) | <.0001 |
Yes | 17 (8.76) | 44 (28.57) | 61 (17.53) | |
Gonorrhea | ||||
No | 187 (96.39) | 134 (87.01) | 321 (92.24) | 0.001 |
Yes | 7 (3.61) | 20 (12.99) | 27 (7.76) | |
Chlamydia | ||||
No | 191 (98.45) | 141 (91.56) | 332 (95.40) | 0.002 |
Yes | 3 (1.55) | 13 (8.44) | 16 (4.60) | |
Number of STIs | ||||
0 | 160 (82.47) | 92 (59.74) | 252 (72.41) | <.0001 |
1 | 29 (14.95) | 40 (25.97) | 69 (19.83) | |
≥2 | 5 (2.58) | 22 (14.29) | 27 (7.76) | |