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Table 3 Treatment related characteristics of HIV infected patients treated at Woldia and Dessie hospitals, 2018

From: Predictors of virological treatment failure among adult HIV patients on first-line antiretroviral therapy in Woldia and Dessie hospitals, Northeast Ethiopia: a case-control study

Variables

Category

Cases(n=154)

Controls (n=154)

p-value for Chi-square test

Frequency (%)

Frequency (%)

Duration on ART

<24 months

8 (5.2)

9 (5.8)

0.781

24-48 months

22 (14.3)

26 (16.9)

>48 months

124 (80.5)

119 (77.3)

Adherence level to ART treatment

Good

89 (57.8)

135 (87.7)

<0.001

Poor

65 (42.2)

19 (12.3)

History of CPT

Yes

139 (90.3)

127 (82.5)

0.046

No

15 (9.7)

27 (17.5)

History of IPT

Yes

8 (5.2)

16 (10.4)

0.089

No

146 (94.8)

138 (89.6)

Regimen at the start of ART

d4t+3TC+NVP

32 (20.8)

26 (16.9)

0.931

AZT+3TC+NVP

46 (29.9)

50 (32.5)

AZT+3TC+EFV

30 (19.5)

30 (19.5)

TDF+3TC+EFV

37 (24)

38 (24.7)

TDF+3TC+NVP

9 (5.8)

10 (6.5)

First line regimen currently

AZT+3TC+NVP

53 (34.4)

58 (37.7)

0.733

AZT+3TC+EFV

32 (20.8)

31 (20)

TDF+3TC+EFV

48 (31.2)

50 (32.5)

TDF+3TC+NVP

21 (13.6)

15 (9.8)

Change of ART regimen or individual drug

Yes

45 (29.2)

47 (30.7)

0.803

No

109 (70.8)

107 (69.5)

History of treatment interruption

Yes

6 (3.9)

4 (2.6)

0.520

No

148 (96.1)

150 (97.4)

  1. CPT Cotrimoxazole Prophylaxis therapy, IPT Isonized Prophylaxis therapy, AZT Zidovudine, d4t Stavudine, TDF Tenofovir, 3TC Lamuvidine, NVP Nevirapine, EFV Efavirnez