Table 1 Cohort Demographic and Clinical Characteristics stratified by body mass index prior to HAART introduction
|  | Total (n = 1612) | Underweight (n = 173) | Normal (n = 1156) | Overweight/ obese (n = 283) | p |
|---|---|---|---|---|---|
Demographic and Clinical Characteristics | |||||
Age | 32 (26–44) | 29 (24–39) | 32 (26–44) | 35 (28–45) | < 0.01 |
Sex | 0.004 | ||||
 Male | 1519 (94.2) | 155 (89.6) | 1102 (95.3) | 262 (92.6) |  |
 Female | 93 (5.8) | 18 (10.4) | 54 (4.7) | 21 (7.4) |  |
Marital status | 0.075 | ||||
 Single | 914 (56.8) | 111 (64.2) | 662 (57.3) | 141 (50.0) |  |
 Married/Partnered | 483 (30.0) | 45 (26.0) | 342 (29.6) | 96 (34.0) |  |
 Divorced/Separated | 196 (12.2) | 14 (8.1) | 140 (12.1) | 42 (14.9) |  |
 Widowed | 17 (1.1) | 3 (1.7) | 11 (1.0) | 3 (1.1) |  |
Ethnics | 0.613 | ||||
 Han | 1390 (86.4) | 153 (88.4) | 991 (85.9) | 246 (87.2) |  |
 Not Han | 218 (13.6) | 20 (11.6) | 162 (14.1) | 36 (12.8) |  |
Education | 0.255 | ||||
 Less than 9 years | 438 (28.9) | 51 (31.1) | 300 (27.8) | 87 (32.5) |  |
 More than 9 years | 1075 (71.1) | 113 (68.9) | 781 (72.2) | 181 (67.5) |  |
Smoking | 0.278 | ||||
 NO | 1000 (62.7) | 112 (65.9) | 723 (63.2) | 165 (58.9) |  |
 YES | 594 (37.3) | 58 (34.1) | 421 (36.8) | 115 (41.1) |  |
Alcohol use | 0.104 | ||||
 NO | 843 (53.3) | 102 (61.1) | 594 (52.3) | 147 (52.7) |  |
 YES | 738 (46.7) | 65 (38.9) | 541 (47.7) | 132 (47.3) |  |
Transmission route | 0.029 | ||||
 Transfusion | 4 (0.2) | 0 (0.0) | 4 (0.3) | 0 (0.0) |  |
 IDU | 6 (0.4) | 2 (1.2) | 2 (0.2) | 2 (0.7) |  |
 MSM | 1292 (80.1) | 134 (77.5) | 945 (81.7) | 213 (75.3) |  |
 HTS | 182 (11.3) | 20 (11.6) | 128 (11.1) | 34 (12.0) |  |
 Unkown | 128 (7.9) | 17 (9.8) | 77 (6.7) | 34 (12.0) |  |
Clinical symptoms | < 0.01 | ||||
 Yes | 231 (14.3) | 51 (29.5) | 157 (13.6) | 23 (8.1) |  |
 No | 1360 (84.4) | 121 (69.9) | 980 (84.8) | 259 (91.5) |  |
 Unkown | 21 (1.3) | 1 (0.6) | 19 (1.6) | 1 (0.4) |  |
Tuberculosis infection | < 0.01 | ||||
 Yes | 95 (5.9) | 26 (15.0) | 62 (5.4) | 7 (2.5) |  |
 No | 1493 (92.7) | 142 (82.1) | 1077 (93.2) | 274 (96.8) |  |
 Unkown | 23 (1.4) | 5 (2.9) | 16 (1.4) | 2 (0.7) |  |
WHO stage | < 0.01 | ||||
 I | 1292 (80.2) | 109 (63.0) | 932 (80.7) | 251 (88.7) |  |
 II | 66 (4.1) | 7 (4.0) | 54 (4.7) | 5 (1.8) |  |
 III | 104 (6.5) | 17 (9.8) | 73 (6.3) | 14 (4.9) |  |
 IV | 149 (9.2) | 40 (23.1) | 96 (8.3) | 13 (4.6) |  |
Laboratory Examination | |||||
Median CD4 (cells/μL) | 243 (139–323) | 183 (40–283) | 243 (144–318) | 271 (181–359) | < 0.01 |
Median CD8 (cells/μL) | 881 (618–1224) | 738 (509–1058) | 890 (625–1233) | 929 (677–1287) | < 0.01 |
Median CD4/CD8 ratio | 0.24 (0.15–0.37) | 0.19 (0.07–0.35) | 0.25 (0.15–0.37) | 0.28 (0.18–0.41) | < 0.01 |
Median viral load (log10copies/mL) | 4.69 (4.25–5.09) | 4.87 (4.35–5.43) (n = 165) | 4.66 (4.25–5.09) (n = 1107) | 4.71 (4.20–4.97) (n = 273) | 0.002 |
Median TC (mmol/L) | 3.92 (3.45–4.51) | 3.80 (3.40–4.35) | 3.89 (3.43–4.50) | 4.11 (3.61–4.63) | 0.002 |
Median TG (mmol/L) | 1.22 (0.84–1.73) | 1.03 (0.75–1.45) | 1.18 (0.82–1.67) | 1.57 (1.09–2.24) | < 0.01 |
Median Glucose (mmol/L) | 5.18 (4.86–5.59) | 4.99 (4.69–5.34) | 5.17 (4.85–5.54) | 5.39 (5.01–5.93) | < 0.01 |
Median hemoglobin (g/L) | 149 (137–158) | 141 (122–153) | 149 (137–157) | 153 (143–162) | < 0.01 |