Variables | Early Detection Group (n = 14) | Late Detection Group (n = 70) | P |
---|---|---|---|
Demographic characteristics | |||
 Age, Median (IQR) | 75.00 (16.25–143.50) | 49.50 (8.49–124.75) | 0.275 |
 Weight, Median (IQR) | 23.00 (8.50–36.25) | 14.50 (7.50–32.75) | 0.506 |
 Male (n, %) | 11 (78.6%) | 44 (62.86%) | 0.262 |
Underlying Conditions | |||
 Hematologic malignancy (n, %) | 2 (14.3%) | 8 (11.43%) | 0.765 |
 Congenital heart disease (n, %) | 4 (28.6%) | 10 (14.29%) | 0.193 |
 Neutropenia (n, %) | 2 (14.3%) | 8 (11.43%) | 0.765 |
 Primary immunodeficiency (n, %) | 2 (14.3%) | 5 (7.14%) | 0.394 |
 Chronic kidney disease (n, %) | 1 (7.1%) | 2 (2.86%) | 0.433 |
Source of infection | |||
 Multiple sitesb | 5 (35.7%) | 19 (27.1%) | 0.519 |
 Pneumonia | 3 (21.4%) | 20 (28.6%) | 0.587 |
 Bone or joint | 0 (0.0%) | 13 (18.6%) | 0.081 |
 Skin or soft tissue | 0 (0.0%) | 9 (12.9%) | 0.158 |
 Primary bacteremia | 0 (0.0%) | 4 (5.7%) | 0.362 |
 Intravenous catheter | 2 (14.3%) | 2 (2.9%) | 0.068 |
 Catheter related infectionc | 1 (7.1%) | 1 (1.4%) | 0.203 |
 Incision | 0 (0.0%) | 2 (2.9%) | 0.525 |
 Endocarditis | 2 (14.3%) | 0 (0.0%) | 0.001 a |
 CNS infection | 1 (7.1%) | 0 (0.0%) | 0.025 a |
APACHE II score ≥ 15 (n, %) | 5 (35.7%) | 22 (31.4%) | 0.755 |
Prior antibiotic exposure (n, %) | 7 (50.0%) | 28 (40.0%) | 0.491 |
 Appropriate antibiotic exposure (n, %) | 1 (7.1%) | 12 (17.1%) | 0.348 |
Immunosuppressants use (n, %) | 6 (42.9%) | 14 (20.0%) | 0.068 |
Nosocomial infection (n, %) | 3 (21.4%) | 11 (15.7%) | 0.603 |
Methicillin-resistance (n, %) | 4 (28.6%) | 25 (35.7%) | 0.610 |
Hypoalbuminemia (n, %) | 1 ((7.1%) | 5 (7.1%) | 1.000 |
Need for Treatments | |||
 Invasive Mechanical ventilation (n, %) | 6 (42.9%) | 12 (17.1%) | 0.033 a |
 Vasoactive agent (n, %) | 7 (50.0%) | 13 (18.6%) | 0.012 a |
Outcomes | |||
 In-hospital mortality (n, %) | 8 (57.1%) | 5 (7.1%) | 0.000 a |
 Septic shock (n, %) | 8 (57.1%) | 13 (18.6%) | 0.002 a |
 Length of hospitalization Median (IQR) | 17.00 (2.75–33.00) | 22.50 (14.75–37.00) | 0.151 |