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Fig. 4 | BMC Infectious Diseases

Fig. 4

From: Construction and analysis of a comprehensive protein interaction network of HCV with its host Homo sapiens

Fig. 4

KEGG Pathway enrichment analysis of top 5 most connected genes shows that the genes are enriched in two hormonal pathways, A. Synthesis and secretion of a steroid hormone, the aldosterone and B. The prolactin hormone which is associated in a vast variety of biological functions within human body. Other pathways in which the set of genes were enriched include Jak-STAT signaling pathway, influenza A, hepatitis C, measles, epstein-barr virus infection and protein processing in endoplasmic reticulum. It should be noted here that color of the bars shows the intensity of the enrichment of the specific genes in a certain pathway. The lighter the color, the most enriched the genes are in that specific pathway. In the above picture, pink color bars shows that genes are enriched in only two pathways and the grey color shows that genes are very less or not enriched in the rest of the processes

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