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Table 1 Socioeconomic and obstetric characteristics of the OCV recipients and placebo recipients among pregnant women

From: Safety of a bivalent, killed, whole-cell oral cholera vaccine in pregnant women in Bangladesh: evidence from a randomized placebo-controlled trial

Characteristics Pregnant during vaccination (Cohort 1) Pregnant after vaccination (Cohort 2)
OCV recipients (n = 231) Placebo recipients (n = 234) p-value OCV recipients (n = 277) Placebo recipients (n = 299) p-value
Median gestational age at screening visit/recruitment– (IQR; weeks) 22 (19, 25) 21 (19, 25.5) 0.541 12 (9, 15) 12 (9, 16) 0.751
Median gestational age at vaccination – (IQR; weeks) 4 (1.79, 7.71) 4.43 (2.14, 8.57) 0.407
Median time of vaccination prior to pregnancy -(IQR; weeks) 4.71 (2.14, 8.14) 5 (2.43, 8.29) 0.408
Exposed to the OCV in the 1st trimester– no. (%) 198 (85.71) 194 (82.91) 0.481    
Mean age (SD; year) 26.27 (5.70) 26.19 (5.70) 0.876 24.92 (5.10) 24.81 (5.26) 0.785
Illiterate– no. (%) 53 (22.94) 49 (20.94) 0.682 39 (14.08) 54 (18.06) 0.236
Diarrhoea within past 6 months prior to baseline census-- no. (%) 24 (10.39) 28 (11.97) 0.695 31 (11.19) 16 (5.35) 0.016
Live in own house – no. (%) 37 (16.02) 34 (14.53) 0.751 59 (21.30) 62 (20.74) 0.949
Live in a household with family size ≤4 – no. (%) 112 (48.48) 108 (46.15) 0.681 112 (40.43) 106 (35.45) 0.252
Live in a household using own tap as the source of drinking water-– no. (%) 15 (6.49) 13 (5.56) 0.818 18 (6.50) 31 (10.37) 0.130
Live in a household with treated drinking water-– no. (%) 127 (54.98) 133 (56.84) 0.756 177 (64.13) 189 (63.21) 0.887
Live in a household using sanitary toilet– no. (%) 156 (67.53) 167 (71.37) 0.425 214 (77.26) 219 (73.24) 0.309
Median time living in the household (IQR; months) 20 (7, 48) 15 (6, 38.5) 0.369 24 (10, 48) 24 (6, 48) 0.683
Live in a household with concrete roof – no. (%) 37 (16.02) 31 (13.25) 0.475 48 (17.33) 70 (23.41) 0.088
Live in a household with concrete wall – no. (%) 161 (69.70) 160 (68.38) 0.835 205 (74.01) 212 (70.90) 0.460
Live in a household using shared kitchen– no. (%) 197 (85.28) 202 (86.32) 0.850 232 (83.75) 253 (84.62) 0.866
Live in a household using shared toilet– no. (%) 206 (89.18) 216 (92.31) 0.315 242 (87.36) 258 (86.29) 0.796
Live in a household with only one room– no. (%) 54 (23.38) 54 (23.08) 1.000 82 (29.60) 77 (25.75) 0.347
Obstetric history
 Had any ANC visita– no. (%) 191 (82.68) 189 (80.77) 0.679 246 (88.81) 267 (89.30) 0.957
 Had ankle swelling– no. (%) 11 (4.76) 18 (7.69) 0.265 15 (5.42) 18 (6.02) 0.894
 Had gestational diabetesb– no. (%) 4 (1.73) 2 (0.85) 0.448 1 (0.36) 4 (1.34) 0.375
 Had gestational hypertensionc– no. (%) 1 (0.43) 4 (1.71) 0.372 4 (1.44) 8 (2.68) 0.387
 Had eclampsia`d– no. (%) 1 (0.43) 0 (0.00) 0.497 3 (1.08) 1 (0.33) 0.356
 Had history of stresse– no. (%) 26 (11.26) 23 (9.83) 0.726 29 (10.47) 38 (12.71) 0.479
 Had previous bad obstetrical historyf– no. (%) 78 (33.77) 76 (32.48) 0.844 102 (36.82) 115 (38.46) 0.749
 Had any chronic disease7– no. (%) 9 (3.90) 6 (2.56) 0.582 11 (3.97) 12 (4.01) 1.000
 Mid-upper arm circumference ≤ 21.5 cm– no. (%) 11 (6.36) 11 (6.79) 1.000 11 (4.76) 13 (5.20) 0.991
  1. aAntenatal care is the routine health control of presumed healthy prengant women without symptoms (screening) to diagnose diseases or complicating obstetric conditions without symptoms and to provide information about lifestyle, pregnancy and delivery
  2. bGestational diabetes is a high blood sugar that develops during pregnancy and usually disappears after giving birth
  3. cGestational hypertension is new hypertension presenting after 20 weeks without significant proteinuria
  4. dA convulsive state; especially: an attack of convulsions during pregnancy or childbirth
  5. eIn a medical or biological context, stress is a physical, mental, or emotional factor that causes bodily or mental tension
  6. fThe term ‘Bad Obstetric History or BOH’ is applied to mothers in whom a previous poor pregnancy outcome is likely to have a bearing on the prognosis of her present pregnancy
  7. 7The term chronic disease applies to a group of diseases that tend to be long lasting and have persistent effects