Characteristics | Pregnant during vaccination (Cohort 1) | Pregnant after vaccination (Cohort 2) | ||||
---|---|---|---|---|---|---|
OCV recipients (nā=ā231) | Placebo recipients (nā=ā234) | p-value | OCV recipients (nā=ā277) | Placebo recipients (nā=ā299) | p-value | |
Median gestational age at screening visit/recruitmentā (IQR; weeks) | 22 (19, 25) | 21 (19, 25.5) | 0.541 | 12 (9, 15) | 12 (9, 16) | 0.751 |
Median gestational age at vaccination ā (IQR; weeks) | 4 (1.79, 7.71) | 4.43 (2.14, 8.57) | 0.407 | ā | ā | ā |
Median time of vaccination prior to pregnancy -(IQR; weeks) | ā | ā | ā | 4.71 (2.14, 8.14) | 5 (2.43, 8.29) | 0.408 |
Exposed to the OCV in the 1st trimesterā no. (%) | 198 (85.71) | 194 (82.91) | 0.481 | Ā | Ā | Ā |
Mean age (SD; year) | 26.27 (5.70) | 26.19 (5.70) | 0.876 | 24.92 (5.10) | 24.81 (5.26) | 0.785 |
Illiterateā no. (%) | 53 (22.94) | 49 (20.94) | 0.682 | 39 (14.08) | 54 (18.06) | 0.236 |
Diarrhoea within past 6āmonths prior to baseline census-- no. (%) | 24 (10.39) | 28 (11.97) | 0.695 | 31 (11.19) | 16 (5.35) | 0.016 |
Live in own house ā no. (%) | 37 (16.02) | 34 (14.53) | 0.751 | 59 (21.30) | 62 (20.74) | 0.949 |
Live in a household with family size ā¤4 ā no. (%) | 112 (48.48) | 108 (46.15) | 0.681 | 112 (40.43) | 106 (35.45) | 0.252 |
Live in a household using own tap as the source of drinking water-ā no. (%) | 15 (6.49) | 13 (5.56) | 0.818 | 18 (6.50) | 31 (10.37) | 0.130 |
Live in a household with treated drinking water-ā no. (%) | 127 (54.98) | 133 (56.84) | 0.756 | 177 (64.13) | 189 (63.21) | 0.887 |
Live in a household using sanitary toiletā no. (%) | 156 (67.53) | 167 (71.37) | 0.425 | 214 (77.26) | 219 (73.24) | 0.309 |
Median time living in the household (IQR; months) | 20 (7, 48) | 15 (6, 38.5) | 0.369 | 24 (10, 48) | 24 (6, 48) | 0.683 |
Live in a household with concrete roof ā no. (%) | 37 (16.02) | 31 (13.25) | 0.475 | 48 (17.33) | 70 (23.41) | 0.088 |
Live in a household with concrete wall ā no. (%) | 161 (69.70) | 160 (68.38) | 0.835 | 205 (74.01) | 212 (70.90) | 0.460 |
Live in a household using shared kitchenā no. (%) | 197 (85.28) | 202 (86.32) | 0.850 | 232 (83.75) | 253 (84.62) | 0.866 |
Live in a household using shared toiletā no. (%) | 206 (89.18) | 216 (92.31) | 0.315 | 242 (87.36) | 258 (86.29) | 0.796 |
Live in a household with only one roomā no. (%) | 54 (23.38) | 54 (23.08) | 1.000 | 82 (29.60) | 77 (25.75) | 0.347 |
Obstetric history | ||||||
āHad any ANC visitaā no. (%) | 191 (82.68) | 189 (80.77) | 0.679 | 246 (88.81) | 267 (89.30) | 0.957 |
āHad ankle swellingā no. (%) | 11 (4.76) | 18 (7.69) | 0.265 | 15 (5.42) | 18 (6.02) | 0.894 |
āHad gestational diabetesbā no. (%) | 4 (1.73) | 2 (0.85) | 0.448 | 1 (0.36) | 4 (1.34) | 0.375 |
āHad gestational hypertensioncā no. (%) | 1 (0.43) | 4 (1.71) | 0.372 | 4 (1.44) | 8 (2.68) | 0.387 |
āHad eclampsia`dā no. (%) | 1 (0.43) | 0 (0.00) | 0.497 | 3 (1.08) | 1 (0.33) | 0.356 |
āHad history of stresseā no. (%) | 26 (11.26) | 23 (9.83) | 0.726 | 29 (10.47) | 38 (12.71) | 0.479 |
āHad previous bad obstetrical historyfā no. (%) | 78 (33.77) | 76 (32.48) | 0.844 | 102 (36.82) | 115 (38.46) | 0.749 |
āHad any chronic disease7ā no. (%) | 9 (3.90) | 6 (2.56) | 0.582 | 11 (3.97) | 12 (4.01) | 1.000 |
āMid-upper arm circumferenceāā¤ā21.5ācmā no. (%) | 11 (6.36) | 11 (6.79) | 1.000 | 11 (4.76) | 13 (5.20) | 0.991 |