Table 3 Characteristics of patients switching an anchor drug class from the first ART regimen from 2011 to 2016
Characteristics | Anchor drug class prescribed in the first ART regimen | ||
|---|---|---|---|
NNRTI (n = 85) | PI (n = 162) | INSTI (n = 22) | |
Age (years) | |||
Mean ± SD | 48.6 ± 11.4 | 43.6 ± 11.8 | 44.7 ± 13.4 |
Range | 24–75 | 23–81 | 27–76 |
Age group (years) | |||
18–39 | 21 (24.7) | 63 (38.9) | 10 (45.5) |
40–59 | 46 (54.1) | 79 (48.8) | 8 (36.4) |
≥ 60 | 18 (21.2) | 20 (12.3) | 4 (18.2) |
Gender, male | 81 (95.3) | 146 (90.1) | 19 (86.4) |
AIDS-defining illnesses | 39 (45.9) | 66 (40.7) | 13 (59.1) |
HIV-related diseases | 22 (25.9) | 33 (20.4) | 6 (27.3) |
Hypertension | 17 (20.0) | 23 (14.2) | 4 (18.2) |
Dyslipidemia | 30 (35.3) | 41 (25.3) | 7 (31.8) |
Hepatitis B/C coinfection | 11 (12.9) | 19 (11.7) | 3 (13.6) |
Diabetes | 26 (30.6) | 36 (22.2) | 3 (13.6) |
Bone disorder | 3 (3.5) | 4 (2.5) | 1 (4.5) |
Vascular disease | 3 (3.5) | 3 (1.9) | 1 (4.5) |
Psychiatric disorders | 11 (12.9) | 20 (12.3) | 2 (9.1) |
Kidney disease | 8 (9.4) | 8 (4.9) | 1 (4.5) |
Malignancy | 2 (2.4) | 9 (5.6) | 1 (4.5) |
History of hospitalization | 11 (12.9) | 26 (16.0) | 9 (40.9) |
Year of ART initiation | |||
2011 | – | 1 (0.6) | – |
2012 | 10 (11.8) | 19 (11.7) | – |
2013 | 14 (16.5) | 28 (17.3) | 3 (13.6) |
2014 | 59 (69.4) | 99 (61.1) | 15 (68.2) |
2015 | 1 (1.2) | 9 (5.6) | 2 (9.1) |
2016 | 1 (1.2) | 6 (3.7) | 2 (9.1) |