NHC | CHB | HBV-related cirrhosis | P value | |
---|---|---|---|---|
Male | 38 (73.1%) | 60 (76.9%) | 55 (75.3%) | ns |
Female | 14 (26.9%) | 18 (23.1%) | 18 (24.7%) | ns |
Age (year) | 41.3 ± 10.05 | 36.0 ± 9.69 | 47.8 ± 11.6*** | < 0.001 |
family HBV-infection history | no | 12/78 | 11/73 | ns |
duration of HBsAg positive (year) | no | 7.6 ± 7.5 | 11.2 ± 9.1* | < 0.05 |
ALT(U/L) | 25.2 ± 6.35 | 277.3 ± 229.6### | 166.3 ± 397.0###*** | < 0.001 |
AST(U/L) | 18.5 ± 3.44 | 106.2 ± 91.9### | 110.37 ± 220.1### | < 0.001 |
TBIL(umol/L) | 13.4 ± 4.61 | 48.62 ± 113.12### | 43.11 ± 85.50###* | < 0.001 |
ALB(g/L) | 45.3 ± 9.62 | 44.6 ± 5.33 | 37.6 ± 3.85#* | < 0.05 |
PT(s) | 12.68 ± 0.68 | 13.73 ± 1.39 | 17.25 ± 7.46##** | < 0.01 |
HBV DNA (log10 IU/ml, Mean ± SEM) | no | 5.870 ± 0.194 | 4.242 ± 0.336*** | < 0.001 |
HA(ng/mL) | 89.2 ± 26.05 | 112.3 ± 133.92 | 228.3 ± 262.9##** | < 0.01 |
LN(ng/mL) | 88.6 ± 28.32 | 77.7 ± 28.68 | 98.89 ± 58.97 | ns |
PC-III(ng/mL) | 76.7 ± 33.56 | 78.2 ± 55.49 | 102.9 ± 86.07 | ns |
C-IV(ng/mL) | 84.08 ± 21.81 | 107.19 ± 112.62 | 120.73 ± 82.93 | ns |