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Table 3 The antimicrobial resistance profile of the main microorganisms isolated from childhood AMES

From: The etiology of acute meningitis and encephalitis syndromes in a sentinel pediatric hospital, Shenzhen, China

Antibiotics

Microorganisms

S. pneumoniae (n = 4)

S. epidermidis (n = 8)

GBS (n = 9)

E. coli (n = 12)

MIC range

(μg/ml)

No. of resistant strains

MIC range

(μg/ml)

No. of resistant strains

MIC range

(μg/ml)

No. of resistant strains

MIC range

(μg/ml)

No. of resistant strains

Penicillin

 amoxicillin

≤ 1

0

–

–

–

–

–

–

 ampicillin

–

–

–

–

≤ 0.25

0

≤ 2- ≥ 32

9

 oxacillin

–

–

≥ 4

8

–

–

–

–

 penicillin

≤ 0.06- ≥ 2

3

≥ 0.5

8

≤ 0.12

0

 

–

Cephalosporins

 cefazolin

–

–

–

–

–

–

≤ 4- ≥ 64

6

 cefepime

–

–

–

–

–

–

≤ 1- ≥ 64

2

 ceftazidime

–

–

–

–

–

–

≤ 1–16

3

 ceftriaxone

≤ 1

0

–

–

–

–

≤ 1- ≥ 64

6

Glycopeptide

 vancomycin

–

–

≤ 2

0

≤ 0.5

0

–

–

Aminoglycoside

 gentamicin

–

–

≤ 0.5

0

–

–

≤ 1- ≥ 16

4

Tetracycline

 tetracycline

4- ≥ 16

3

≤ 2

0

≥ 16

9

–

–

Fluoroquinolone

 ciprofloxacin

–

–

≤ 2

0

≤ 0.5

0

≤ 0.25- ≥ 4

5

 levofloxacin

≤ 1

0

≤ 2

0

≤ 1

0

≤ 0.25- ≥ 8

5

Lincosamide

 clindamycin

–

–

≤ 0.25- ≥ 8

3

≥ 0.5

9

–

–

Folate pathway inhibitor

 trimethoprim/sulfamethoxazole

20–80

3

≤ 10- ≥ 320

5

–

–

≤ 20- ≥ 320

8

β-lactam/β-lactamase inhibitor

 ampicillin/sulbactam

–

–

–

–

–

–

≤ 2- ≥ 32

6

Monobactam

 aztreonam

–

–

–

–

–

–

≤ 1- ≥ 64

3

Carbapenem

        

 imipenem

–

–

–

–

–

–

≤ 1

0

  1. MIC minimum inhibitory concentration
  2. - not tested