Table 1 Clinical characteristic of influenza associated hospitalizations during the 2017-2018 influenza and 2011-2017 seasons
From: Clinical characteristics and outcomes during a severe influenza season in China during 2017–2018
Variables n (%) | 2011-2017 (n = 169) | 2017-2018 (n = 289) | P value |
|---|---|---|---|
Gender-male | 102 (60.4) | 169 (58.5) | 0.693 |
Age groups | |||
<14 years | 22 (13.0) | 37 (12.8) | |
14- years | 81 (47.9) | 129 (44.6) | 0.751 |
>=60 years | 66 (39.1) | 123 (42.6) | |
Co-morbidities | |||
Cardiovascular diseases | 55 (32.5) | 120 (41.5) | 0.056 |
Respiratory diseases | 17 (5.9) | 24 (8.3) | 0.526 |
Chronic renal diseases | 11 (6.5) | 22 (7.6) | 0.659 |
Chronic liver diseases | 11 (6.5) | 27 (9.3) | 0.289 |
Diabetes mellitus | 18 (10.7) | 29 (10.0) | 0.834 |
Cancer and hematological diseases | 56 (33.1) | 83 (28.7) | 0.321 |
Stroke and Neuromuscular diseases | 15 (8.9) | 17 (5.9) | 0.225 |
Immunosuppressant | 19 (11.2) | 38 (13.1) | 0.551 |
Pregnancy | 0 (0) | 2 (0.7) | 0.533 |
Postmortum within 30 days after delivery | 0 (0) | 1 (0.3) | 1.000 |
Current smoking | 20 (6.9) | 57 (19.7)* | 0.029 |
Received seasonal or influenza A (H1N1) vaccination | 0 (0) | 0 (0.0) | NA |
Symptoms and Lab findings | |||
Fever (temp >=38) | 159 (94.1) | 257 (88.9) | 0.065 |
Cough | 141 (83.4) | 247 (85.5) | 0.559 |
Dyspnea | 17 (5.9) | 50 (17.3)* | 0.034 |
Hemoptysis | 5 (3.0) | 14 (4.8) | 0.329 |
CNS symptom | 2 (1.2) | 11 (3.8) | 0.180 |
WBC<4 | 50 (29.6) | 70 (24.2) | 0.266 |
L%<20% | 97 (59.1) | 162 (56.1) | 0.192 |
Platelet<100 | 36 (65.0) | 46 (15.9) | 0.286 |
ALT >40 | 36 (21.4) | 86 (30.9)* | 0.029 |
AST >40 | 54 (32.3) | 109 (39.4) | 0.137 |
LDH >300 | 48 (35.6) | 108 (42.7) | 0.172 |
CK>200 | 14 (10.4) | 54 (21.3)** | 0.007 |
CRP>8 | 121 (79.1) | 196 (75.1) | 0.355 |
ESR >20 | 67 (39.6) | 98 (60.1) | 0.420 |
Treatment on admission | |||
Antibiotics use | 160 (94.7) | 258 (89.3)* | 0.048 |
21 (12.4) | 33 (11.4) | 0.747 | |
Oseltamivir | 147 (87.0) | 222 (76.8)** | 0.008 |
Traditional Chinese Medicine | 28 (16.6) | 64 (22.1) | 0.151 |
Glucocorticoids | 64 (37.9) | 134 (46.4) | 0.077 |
Outcome | |||
Total In-hospital fatality | 2 (1.2) | 19 (6.6)** | 0.008 |