Table 3 Characteristics of inpatients with influenza among different age groups during the 2011–2017 and 2017–2018 influenza seasons
From: Clinical characteristics and outcomes during a severe influenza season in China during 2017–2018
Variables n (%) | < 14 years | 14–59 years | > = 60 years | |||
|---|---|---|---|---|---|---|
2011–2017 (n = 22) | 2017–2018 (n = 37) | 2011–2017 (n = 81) | 2017–2018 (n = 129) | 2011–2017 (n = 66) | 2017–2018 (n = 123) | |
Gender-male | 12 (54.5) | 16 (43.2) | 41 (50.6) | 71 (55.0) | 49 (74.2) | 82 (66.7) |
Co-morbidities | ||||||
Cardiovascular diseases | 1 (4.5) | 1 (2.7) | 17 (21.0) | 37 (28.7) | 37 (56.1) | 82 (66.7) |
Respiratory diseases | 0 (0) | 0 (0) | 3 (3.7) | 2 (1.6) | 14 (21.2) | 22 (17.9) |
Chronic renal diseases | 0 (0) | 0 (0) | 5 (6.2) | 11 (8.5) | 6 (9.1) | 11 (8.9) |
Chronic liver diseases | 0 (0) | 0 (0) | 8 (9.9) | 14 (10.9) | 3 (4.5) | 13 (10.6) |
Diabetes mellitus | 0 (0) | 0 (0) | 5 (6.2) | 9 (7.0) | 13 (19.7) | 20 (16.3) |
Cancer and hematological diseases | 3 (13.6) | 28 (34.6) | 39 (30.2) | 25 (37.9) | 37 (30.1) | |
Stroke and Neuromuscular diseases | 0 (0) | 0 (0) | 4 (4.9) | 2 (1.6) | 11 (16.7) | 15 (12.2) |
Immunosuppressant | 0 (0) | 0 (0) | 13 (16.5) | 21 (16.3) | 6 (9.1) | 17 (13.8) |
Pregnancy | 0 (0) | 0 (0) | 0 (0) | 2 (1.6) | 0 (0) | 0 (0) |
Postmortum within 30 days after delivery | 0 (0) | 0 (0) | 0 (0) | 1 (0.8) | 0 (0) | 0 (0) |
Current smoking | 0 (0) | 0 (0) | 7 (8.6) | 26 (20.2)* | 13 (19.7) | 31 (25.2) |
Received seasonal or influenza A (H1N1) vaccination | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
Symptoms and Lab findings | ||||||
Fever (temp > = 38) | 21 (95.5) | 37 (100.0) | 79 (97.5) | 120 (93.0) | 59 (89.4) | 100 (81.3) |
Cough | 17 (77.3) | 32 (86.5) | 64 (79.0) | 107 (82.9) | 60 (90.1) | 108 (87.8) |
Dyspnea | 0 (0) | 3 (8.1) | 6 (7.4) | 20 (15.5) | 11 (16.7) | 27 (22.0) |
Hemoptysis | 0 (0) | 0 (0) | 3 (3.7) | 9 (7.0) | 2 (3.0) | 5 (4.1) |
CNS symptom | 0 (0) | 0 (0) | 1 (1.2) | 4 (3.1) | 1 (1.5) | 7 (5.7) |
WBC < 4 (× 109/L) | 5 (22.7) | 8 (21.6) | 29 (35.8) | 40 (31.0) | 16 (24.2) | 22 (17.9) |
L% < 20% | 4 (18.2) | 9 (25.7) | 51 (63.0) | 67 (51.9) | 42 (63.6) | 86 (69.9) |
Platelet< 100 (× 109/L) | 1 (4.5) | 2 (5.4) | 18 (22.2) | 22 (17.1) | 17 (25.8) | 22 (17.9) |
ALT > 40 | 1 (4.5) | 4 (11.1) | 20 (24.7) | 48 (38.1) | 15 (22.7) | 34 (29.3) |
AST > 40 | 12 (57.1) | 22 (64.7) | 24 (30.0) | 50 (40.0) | 18 (27.3) | 37 (31.4) |
LDH > 300 | 15 (75.0) | 25 (73.5) | 19 (33.9) | 43 (38.4) | 14 (23.7) | 40 (37.4) |
CK > 200 | 4 (21.1) | 10 (29.4) | 4 (7.1) | 26 (23.0)* | 6 (10.2) | 18 (17.0) |
CRP > 8 | 5 (31.3) | 10 (32.3) | 60 (81.1) | 95 (79.8) | 56 (88.9) | 91 (82.0) |
ESR > 20 | 2 (20.0) | 4 (25.0) | 30 (57.7) | 46 (59.7) | 35 (85.4) | 48 (68.6)* |
Treatment on admission | ||||||
Antibiotics use | 19 (86.4) | 30 (81.1) | 76 (93.8) | 118 (91.5) | 65 (98.5) | 110 (89.4)* |
Mechanical ventilation | 1 (4.5) | 0 (0) | 9 (11.1) | 13 (10.1) | 11 (16.7) | 20 (16.3) |
Oseltamivir | 8 (36.4) | 27 (73.0) | 76 (93.8) | 99 (76.7)** | 63 (95.5) | 96 (78.0)** |
Traditional Chinese Medicine | 2 (9.1) | 6 (16.2) | 15 (18.5) | 38 (29.5) | 11 (16.7) | 20 (16.3) |
Glucocorticoids | 2 (9.1) | 7 (18.9) | 37 (45.7) | 65 (50.4) | 25 (37.9) | 62 (50.4) |
Outcome | ||||||
In-hospital fatality | 0 (0) | 0 (0) | 1 (1.2) | 6 (4.7) | 1 (1.5) | 13 (10.6)* |