Table 2 Factors associated with active TB incidence in follow-up individuals
# of individuals | TB events/follow-up person-years | IRa(95% CI) | P for chi-square test | Univariate Cox regression | Multivariate Cox regression | |||
|---|---|---|---|---|---|---|---|---|
HR (95% CI) | P value | Adjusted HR(95% CI) | P value | |||||
Sex | 0.01 | |||||||
Female | 30941 | 5/61881 | 8.08 (2.62~18.86) | Reference | Reference | |||
Male | 36351 | 21/72694 | 28.89 (17.88~44.17) | 3.576 (1.348~9.483) | 0.01 | 3.593 (1.354~9.537) | 0.01 | |
Ethnicity | 0.86 | |||||||
Han | 60086 | 23/120164 | 19.14 (12.12~28.73) | Reference | Reference | |||
Others | 7206 | 3/14411 | 20.82 (4.29~60.85) | 1.088 (0.3266~3.622) | 0.89 | |||
Region | 0.21 | |||||||
East | 33692 | 14/67377 | 20.78 (11.35~34.87) | Reference | Reference | |||
Middle | 17069 | 3/34138 | 8.79 (1.81~25.69) | 0.423 (0.121~1.472) | 0.17 | |||
West | 16531 | 9/33060 | 27.22 (12.44~51.70) | 1.310 (0.567~3.027) | 0.52 | |||
TST response (induration size, mm) | < 0.001 | |||||||
0~4 | 51963 | 13/103923 | 12.51 (6.65~21.40) | Reference | Reference | |||
5~9 | 7308 | 2/14615 | 13.68 (1.66~49.44) | 1.094 (0.247~4.848) | 0.91 | 1.094 (0.247~4.846) | 0.91 | |
10~14 | 4217 | 4/8431 | 47.44 (12.90~121.50) | 3.794 (1.237~11.635) | 0.02 | 3.644 (1.188~11.179) | 0.02 | |
15~19 | 2918 | 5/5834 | 85.70 (27.77~200.03) | 6.853 (2.443~19.223) | < 0.001 | 6.832 (2.436~19.163) | < 0.001 | |
≥ 20 | 886 | 2/1772 | 112.87 (13.66~407.79) | 9.032 (2.038~40.025) | 0.004 | 9.768 (2.203~43.315) | 0.003 | |