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Table 5 Clinical data and outcome according to survival status in hospital

From: Clinical parameters and outcomes of necrotizing soft tissue infections secondary to gastrointestinal fistulas

 

Survivors (n = 24)

No-Survivors (n = 15)

P

Gender, (Male), n (%)

22 (91.7)

8 (53.3)

0.028

Age (years), mean (SD)

42.5 ± 13.4

54.9 ± 19.9

0.025

BMI (kg/m 2), mean (SD)

20.7 ± 2.1

20.0 ± 1.5

0.230

APACHE score on admission, mean (SD)

10.4 ± 3.0

13.5 ± 4.0

0.013

Etiology, n (%)

 Trauma

15 (62.5)

10 (66.7)

0.792

 Tumor

5 (20.8)

4 (26.7)

0.674

 Other

3 (12.5)

2 (13.3)

0.940

Shock on admission, n (%)

10 (41.7)

11 (73.3)

0.054

Positive blood cultures, n (%)

8 (33.3)

9 (60.0)

0.102

Multiple fistulas, n (%)

6 (25.0)

10 (66.7)

0.010

The Laboratory data on admission, mean (SD)

 C-Reactive Protein (CRP) (mg/L)

92.5 ± 70.3

173.4 ± 50.5

0.001

 White blood cell count (109/L)

12.0 ± 4.0

10.4 ± 2.7

0.126

 Platelet count (109/L)

217.6 ± 56.3

110.8 ± 57.9

< 0.001

 Hemoglobin (g/dl)

96.9 ± 13.2

110.3 ± 9.7

0.001

Wound culture, n (%)

 Monomicrobial infection

8 (33.3)

2 (13.3)

0.164

 Polymicrobial infection

9 (37.5)

13 (86.7)

0.003

 Klebsiella pneumoniae

2 (8.3)

12 (80.0)

< 0.001

 Fungi

0 (0)

4 (26.7)

0.008

 Multidrug-resistant organisms

7 (28.0)

11 (73.3)

0.007

Management, n (%)

 Open abdomen

5 (20.8)

3 (20.0)

0.950

 NPWT

21 (87.5)

12 (80.0)

0.528

 Hyperbaric oxygen

1 (4.2)

1 (6.7)

0.731

Source control< 48 h, n (%)

17 (63.0)

5 (33.3)

0.022

  1. Data are reported as number of patients (%) or mean ± SD. Abbreviations: BMI Body mass index, APACHE Acute physiology and chronic health evaluation score, NPWT Negative pressure wound therapy