Characteristics | MDR n (%) n = 41 (28.7) | Non-MDR n (%) n = 102 (71.3) | p-value | OR (95% CI) |
---|---|---|---|---|
Demographic data | ||||
Male sex | 31 (75.6) | 57 (55.9) | 0.03 | 2.45 (1.09–5.52) |
Age groups (years), median (1 qt–3 qt) | 63 (51–72) | 57 (38–69) | 0.03+ | – |
0–15 | 0 (0.0) | 6 (5.9) | 0.12 | – |
16–30 | 4 (9.8) | 11 (10.8) | 0.56 | 0.89 (0.26–2.99) |
31–59 | 11 (26.8) | 38 (37.3) | 0.23 | 0.61 (0.28–1.37) |
≥60 | 26 (63.4) | 47 (46.1) | 0.06 | 2.02 (0.96–4.27) |
Comorbidities | ||||
Charlson score, median (1 qt–3 qt) (n = 134)* | 2.5 (2–4) | 2 (2–3) | 0.10 | – |
≥2 (n = 134) | 20 (50.0) | 39 (41.5) | 0.37 | 1.41 (0.67–2.97) |
Congestive heart failure (n = 134) | 3 (7.5) | 5 (5.3) | 0.45 | 1.44 (0.33–6.35) |
Cerebrovascular disease (n = 134) | 5 (12.5) | 11 (11.7) | 0.55 | 1.08 (0.35–3.33) |
Liver disease | 7 (17.5) | 5 (5.3) | 0.02 | 3.78 (1.12–12.73) |
Kidney disease | 6 (15.0) | 21 (22.3) | 0.33 | 0.61 (0.23–1.66) |
History of malignancy | 16 (40.0) | 42 (44.7) | 0.62 | 0.82 (0.39–1.76) |
Metastatic disease | 7 (17.5) | 16 (17.0) | 0.95 | 1.03 (0.39–2.75) |
HIV/AIDS | 1 (2.5) | 0 (0.0) | 0.12 | – |
Previous antimicrobial use (n = 80) | 29 (70.7) | 51 (50.0) | 0.02 | 2.41 (1.11–5.25) |
Prophylactic | 8 (19.5) | 21 (20.6) | 0.88 | 0.93 (0.37–2.32) |
Therapeutic | 26 (63.4) | 43 (42.2) | 0.02 | 2.37 (1.12–5.02) |
Clinical information | ||||
Hospitalized in prior 6 months (n = 140) | 26 (65.0) | 54 (54.0) | 0.24 | 1.58 (0.74–3.38) |
Long hospital stay (> 14 days) | 30 (73.2) | 70 (68.6) | 0.59 | 1.2 (0.55–2.79) |
Users of Health Insurance | 31 (75.6) | 73 (71.6) | 0.62 | 1.23 (0.54–2.94) |
Type of BSI | ||||
Primary | 24 (58.5) | 56 (54.9) | 0.69 | 1.16 (0.56–2.41) |
Secondary (n = 63) | 17 (41.5) | 46 (45.1) | 0.69 | 1.16 (0.56–2.41) |
Urinary tract (n = 29) | 7 (41.2) | 22 (45.8) | 0.74 | 0.82 (0.27–2.53) |
Respiratory tract (n = 17) | 5 (29.4) | 12 (25.0) | 0.72 | 1.25 (0.37–4.28) |
Others (n = 19) | 5 (29.4) | 14 (29.2) | 0.98 | 1.02 (0.30–3.41) |
Location of acquisition | ||||
Community-associated (n = 6) | 1 (2.4) | 5 (4.9) | 0.45 | 0.48 (0.05–4.28) |
Community-onset, healthcare associated (n = 44) | 11 (26.8) | 33 (32.4) | 0.51 | 0.76 (0.34–1.71) |
Hospital-onset, healthcare associated (n = 93) | 29 (70.7) | 64 (62.7) | 0.36 | 1.43 (0.65–3.14) |
Organisms (n = 170)** | ||||
Escherichia coli (n = 50) | 12 (24.5) | 38 (31.4) | 0.37 | 0.70 (0.33–1.50) |
Klebsiella pneumoniae (n = 50) | 27 (55.1) | 23 (19.0) | <0.001 | 5.23 (2.53–0.77) |
Serratia marcescens (n = 15) | 1 (2.0) | 14 (11.6) | 0.04 | 0.15 (0.02–1.24) |
Enterobacter cloacae (n = 13) | 3 (6.1) | 10 (8.3) | 0.45 | 0.72 (0.19–2.75) |
Pseudomonas aeruginosa (n = 12) | 2 (4.1) | 10 (8.3) | 0.28 | 0.47 (0.09–2.24) |
Acinetobacter baumannii (n = 6) | 4 (8.2) | 2 (1.7) | 0.06 | 5.29 (0.93–9.88) |
Others*** (n = 24) | 0 (0) | 24 (19.8) | <0.001 | – |
Polymicrobial BSI (n = 22)Ω | 9 (18.4) | 13 (10.7) | 0.18 | 1.87 (0.74–4.71) |