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Table 1 Patient characteristics and laboratory data

From: Serum-based diagnosis of Pneumocystis pneumonia by detection of Pneumocystis jirovecii DNA and 1,3-β-D-glucan in HIV-infected patients: a retrospective case control study

 

PCP

no PCP

HIV-infected

(n = 26)

HIV-infected

(n = 21)

Blood donors

(n = 18)

Age, yrs., median (range)

47 (25–70)

38 (23–64)

46 (18–59)

Females, n (%)

9 (35)

10 (48)

7 (39)

CD4+ cell count, cells/uL, median (range)

35 (0–460)

50 (0–170)

Pj PCR in serum

 Patients with positive results, n (%)

26 (100)

6 (29)

0 (0)

 Ct value, n, median (range)

29 (25–40)b

38 (32–42)

BG in serum (pg/ml)

 Patients with BG ≥80

24 (96)c

6 (29)

0 (0)

 Patients with BG ≥200

23 (92)c

3 (14)

0 (0)

 BG, median (range)

1328 (50–2000)c

50 (50–2000)

50 (50–58)

  1. PCP Pneumocystis jirovecii pneumonia, Ct cycle threshold, BG 1,3-ß-D-glucan
  2. aSerum samples collected at hospital admission due to newly diagnosed HIV-infection
  3. bThe Ct values from three patients with PCP were excluded since their samples were diluted 1:2 prior to analysis
  4. cOne sample from a patient with PCP was not analyzed for BG due to insufficient volume of serum