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Table 4 HIV-infected control patients with positive Pj PCR in serum

From: Serum-based diagnosis of Pneumocystis pneumonia by detection of Pneumocystis jirovecii DNA and 1,3-β-D-glucan in HIV-infected patients: a retrospective case control study

Pat

CD4 cell count (cells/uL)

Criteria of the PCP reference standard of this study

Outcome

Index tests

Respiratory symptoms

Radiologic findings

Hypoxia

Pj analysis respiratory specimen

TMP-SMX

Other lung infection

BG (pg/ml)

Pj PCR in serum Ct value

1

100

Dry cough

Unknown

Unknown

Unknown

No

No

Survival

> 2000

32

2

30

Dry cough

Discrete interstitial opacity

Unknown

Unknown

Prophylaxis dose

No

Survival

807

33

3

10

Dry cough

Normal

Unknown

Unknown

Nob

No

Survival

< 50

39

4

80

Dyspnea

Discrete GGO

Unknown

PCR nega

No

No

Survival

60

38

5

50

Productive cough and dyspnea

Normal

No

PCR posa

Prophylaxis dose

No

Survival

177

42

6

50

No

Normal

No

Unknown

No

No

Survival

< 50

39

  1. PCP Pneumocystis jirovecii pneumonia, Pj Pneumocystis jirovecii, TMP-SMX trimethoprim–sulfamethoxazole, BG 1,3-ß-D-glucan, Ct Cycle threshold, GGO ground glass opacity
  2. For patients where Pj analysis, radiological exam or measurement of SpO2 was not performed, the data is noted as unknown
  3. aPCR on sputum samples
  4. breceived treatment for toxoplasmosis with pyrimethamine and sulphonamide