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Table 3 Erythromycin and tetracycline resistance phenotype and genotype in 45 Streptococcus gallolyticus subsp. pasteurianus isolates

From: Microbiological and clinical characteristics of Streptococcus gallolyticus subsp. pasteurianus infection in China

Erythromycin phenotype

Clindamycin MIC (μg/mL)

Erythromycin MIC (μg/mL)

Erythromycin resistance genotype

Tetracycline MIC (μg/mL)

Tetracycline phenotype

Tetracycline resistance genotype

No. of isolates

cMLSB

> 1

> 4

erm(A)/erm(B)

> 8

R

tet(M)/tet(L)

2

cMLSB

> 1

> 4

erm(A)/erm(B)

> 8

R

tet(M)/tet(O)

1

cMLSB

> 1

> 4

erm(A)/erm(B)

> 8

R

tet(L)/tet(O)

1

cMLSB

> 1

> 4

erm(A)/erm(B)

> 8

R

tet(O)

3

cMLSB

> 1

> 4

erm(B)

4

I

Negative

1

cMLSB

> 1

> 4

erm(B)

> 8

R

tet(L)

8

cMLSB

> 1

> 4

erm(B)

> 8

R

tet(L)/tet(O)

1

cMLSB

> 1

> 4

erm(B)

> 8

R

tet(M)/tet(L)

1

cMLSB

> 1

> 4

erm(B)

> 8

R

tet(M)/tet(O)

1

cMLSB

> 1

> 4

erm(B)

> 8

R

tet(O)

7

cMLSB

> 1

> 4

erm(B)

> 8

R

tet(L)/tet(O)

5

cMLSB

> 1

> 4

erm(B)

> 8

R

tet(O)/tet(L)/tet(M)

1

cMLSB

> 1

> 4

erm(B)/mef(A/E)

> 8

R

tet(L)

1

cMLSB

> 1

> 4

erm(B)/mef(A/E)

> 8

R

tet(O)/tet(L)

3

cMLSB

> 1

> 4

erm(B)/erm(T)

> 8

R

tet(M)/tet(O)

1

cMLSB

> 1

> 4

erm(B)/erm(T)

> 8

R

tet(O)/tet(L)

1

cMLSB

> 1

> 4

erm(B)/erm(T)

> 8

R

tet(L)

1

cMLSB

> 1

> 4

mef(A/E)

> 8

R

tet(O)/tet(L)

1

S

0.125

≤0.0625

Negative

> 8

R

tet(L)

1

S

0.0625

≤0.0625

Negative

> 8

R

tet(L)

1

S

0.0625

≤0.0625

Negative

> 8

R

tet(O)/tet(L)

1

S

0.0625

≤0.0625

Negative

≤0.5

S

Negative

2

  1. cMLSB, constitutive macrolide-lincosamide-streptogramin B resistance; S/I/R: the isolates susceptible/intermediate/resistant to macrolide or tetracycline