Variable | Total patients (n = 97) | Sepsis (n = 51) | Septic shock (n = 46) | Controls(n = 45) |
---|---|---|---|---|
Age, median (range) | 75 (42–98) | 76 (42–98) | 74 (42–96) | 68 (37–81) |
Sex, n (%) | ||||
 Male | 54 (56) | 28 (55) | 26 (57) | 25 (56) |
 Female | 43 (44) | 23 (45) | 20 (43) | 20 (44) |
Infection site, n (%) | ||||
 Respiratory | 63 (64.9) | 33 (64.7) | 30 (65.2) | – |
 Genitourinary | 32 (33.0) | 19 (37.3) | 13 (28.3) | – |
 Cardiovascular | 3 (3.1) | 0 (0.0) | 3 (6.5) | – |
 Gastrointestinal | 2 (2.1) | 0 (0.0) | 2 (4.3) | – |
 Musculoskeletal | 2 (2.1) | 1 (2.0) | 1 (2.2) | – |
 Central nervous | 1 (1.0) | 0 (0.0) | 1 (2.2) | – |
 Hepatobiliary | 1 (1.0) | 0 (0.0) | 1 (2.2) | – |
 Skin and soft tissue | 1 (1.0) | 1 (2.0) | 0 (0.0) | – |
 Unknown | 5 (5.2) | 2 (3.9) | 3 (6.5) | – |
Underlying disease | ||||
 Coronary artery disease | 11 (11.3) | 5 (9.8) | 6 (13.0) | – |
 Malignancy | 10 (10.3) | 4 (7.8) | 6 (13.0) | – |
 Rheumatic disease | 4 (4.1) | 2 (3.9) | 2 (4.3) | – |
SOFA score, median (IQR) | 8 (4–11) | 6 (3–9) | 10 (6–13) | – |
APACHE II score, median (IQR) | 21 (13–30) | 18 (10–27) | 25 (16–35) | – |
Laboratory value,median (IQR) or mean ± SEM | ||||
 Procalcitonin (ng/mL) | 1.6 (0.5–10.7) | 0.3 (0.2–1.2) | 3.4 (1.6–20.3) |  |
 CRP (mg/dL) | 10 (6–20) | 10 (5–20) | 11 (7–21) |  |
 Lactate (mmol/L) | 3.6 (2.6–4.6) | 1.9 (1.1–2.8) | 5.5 (3.6–7.5) |  |
 Creatinine (mg/dL) | 2.5 ± 0.2 | 2.1 ± 0.2 | 2.9 ± 0.2 |  |
 Bilirubin (mg/dL) | 2.2 ± 0.4 | 1.7 ± 0.3 | 2.8 ± 0.5 |  |
 Platelet (× 1000/μL) | 203 ± 12.4 | 251 ± 14.3 | 153 ± 10.6 |  |
Positive blood cultures, n (%) | 75 (77.3) | 35 (68.6) | 40 (87.0) | – |
ICU days, median (IQR) | 9 (5–14) | 8 (4–11) | 11 (7–16) | – |
Length of stay, median (IQR) | 13 (8–18) | 11 (7–16) | 15 (9–19) | – |