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Table 1 Baseline Characteristics of the Study Population

From: Diagnostic and prognostic value of interleukin-6, pentraxin 3, and procalcitonin levels among sepsis and septic shock patients: a prospective controlled study according to the Sepsis-3 definitions

Variable

Total patients (n = 97)

Sepsis (n = 51)

Septic shock (n = 46)

Controls(n = 45)

Age, median (range)

75 (42–98)

76 (42–98)

74 (42–96)

68 (37–81)

Sex, n (%)

 Male

54 (56)

28 (55)

26 (57)

25 (56)

 Female

43 (44)

23 (45)

20 (43)

20 (44)

Infection site, n (%)

 Respiratory

63 (64.9)

33 (64.7)

30 (65.2)

–

 Genitourinary

32 (33.0)

19 (37.3)

13 (28.3)

–

 Cardiovascular

3 (3.1)

0 (0.0)

3 (6.5)

–

 Gastrointestinal

2 (2.1)

0 (0.0)

2 (4.3)

–

 Musculoskeletal

2 (2.1)

1 (2.0)

1 (2.2)

–

 Central nervous

1 (1.0)

0 (0.0)

1 (2.2)

–

 Hepatobiliary

1 (1.0)

0 (0.0)

1 (2.2)

–

 Skin and soft tissue

1 (1.0)

1 (2.0)

0 (0.0)

–

 Unknown

5 (5.2)

2 (3.9)

3 (6.5)

–

Underlying disease

 Coronary artery disease

11 (11.3)

5 (9.8)

6 (13.0)

–

 Malignancy

10 (10.3)

4 (7.8)

6 (13.0)

–

 Rheumatic disease

4 (4.1)

2 (3.9)

2 (4.3)

–

SOFA score, median (IQR)

8 (4–11)

6 (3–9)

10 (6–13)

–

APACHE II score, median (IQR)

21 (13–30)

18 (10–27)

25 (16–35)

–

Laboratory value,median (IQR) or mean ± SEM

 Procalcitonin (ng/mL)

1.6 (0.5–10.7)

0.3 (0.2–1.2)

3.4 (1.6–20.3)

 

 CRP (mg/dL)

10 (6–20)

10 (5–20)

11 (7–21)

 

 Lactate (mmol/L)

3.6 (2.6–4.6)

1.9 (1.1–2.8)

5.5 (3.6–7.5)

 

 Creatinine (mg/dL)

2.5 ± 0.2

2.1 ± 0.2

2.9 ± 0.2

 

 Bilirubin (mg/dL)

2.2 ± 0.4

1.7 ± 0.3

2.8 ± 0.5

 

 Platelet (× 1000/μL)

203 ± 12.4

251 ± 14.3

153 ± 10.6

 

Positive blood cultures, n (%)

75 (77.3)

35 (68.6)

40 (87.0)

–

ICU days, median (IQR)

9 (5–14)

8 (4–11)

11 (7–16)

–

Length of stay, median (IQR)

13 (8–18)

11 (7–16)

15 (9–19)

–

  1. SOFA sequential organ-failure assessment, IQR interquartile range, APACHE acute physiology and chronic health evaluation, CRP C-reactive protein, SEM standard error of the mean, ICU intensive care unit