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Table 5 Discriminating performance of the combined marker (IL-6 + PTX3), IL-6, and PTX3 for septic shock

From: Diagnostic and prognostic value of interleukin-6, pentraxin 3, and procalcitonin levels among sepsis and septic shock patients: a prospective controlled study according to the Sepsis-3 definitions

Biomarkers

AUC (95% CI)

p

Cut-off

Sensitivity (%)

Specificity (%)

IL-6 + PTX3

0.806 (0.719–0.894)

< 0.001

52.0 (score)

82.7

71.1

IL-6

0.795 (0.702–0.883)

< 0.001

348.92 (pg/mL)

76.1

78.4

PTX3

0.703 (0.603–0.812)

0.001

58.28 (ng/mL)

56.5

76.5

  1. AUC area under the curve, CI confidence interval, IL-6 interleukin-6, PTX3 pentraxin 3