Table 1 Compared TB-SPRINT 59-Plex Beamedex® results for rifampin and isoniazid resistance detection with BACTEC™ MGIT™ 960 system among the three sites evatuated, and Genotype®MTBDRplusbetween with BACTEC™ MGIT™ 960 system
From: Multicenter evaluation of TB-SPRINT 59-Plex Beamedex®: accuracy and cost analysis
BACTEC™ MGIT™ 960 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
S | R | SE | SP | PPV | NPV | A | K* | ||||
TB-SPRINT | FIOCRUZ | RIF n=58 | S | 21 | 2 | 92.8 | 70 | 74.2 | 91.3 | 81 | 0.623 |
R | 9 | 26 | |||||||||
INH n=69 | S | 32 | 4 | 88.5 | 94.1 | 93.9 | 88.9 | 91.3 | 0.826 | ||
R | 2 | 31 | |||||||||
UFRJ | RIF n=57 | S | 47 | 3 | 70 | 100 | 100 | 94 | 94.7 | 0.794 | |
R | 0 | 7 | |||||||||
INH n=83 | S | 51 | 3 | 90 | 96.2 | 93.1 | 94.1 | 93.9 | 0.869 | ||
R | 2 | 27 | |||||||||
UFMG | RIF n=78 | S | 45 | 2 | 93.1 | 91.8 | 87.9 | 95.7 | 92.3 | 0.838 | |
R | 4 | 27 | |||||||||
INH n=89 | S | 51 | 5 | 86.1 | 96.2 | 93.9 | 91 | 92.1 | 0.835 | ||
R | 5 | 28 | |||||||||
MTBDRplus | RIF n=105 | S | 69 | 1 | 97.2 | 100 | 100 | 98.5 | 99 | 0.979 | |
R | 0 | 35 | |||||||||
INH n=105 | S | 69 | 6 | 83.3 | 100 | 100 | 92 | 94.2 | 0.868 | ||
R | 0 | 30 | |||||||||