Table 1 Association analysis of TNF-α, IL-12 and IL-13 gene polymorphisms and brucellosis

TNF-α (− 238 G/A)

G/G

10 (9.3)

13 (12.2)

1.00

A/G

97 (90.7)

94 (87.8)

0.75 (0.31–1.78)

A/A

0

0

–

Allele

A

97 (45)

120 (56)

0.927 (0.633–1.358)

G

117 (55)

94 (44)

IL-12 (+1188 A/C)

Codominant

C/C

22 (20.6)

29 (27.1)

1.00

A/C

78 (72.9)

66 (61.7)

0.64 (0.34–1.22)

A/A

7 (6.5)

12 (11.2)

1.30 (0.44–3.85)

Dominant

C/C

22 (20.6)

29 (27.1)

1.00

A/C-A/A

85 (79.4)

78 (72.9)

0.70 (0.37–1.31)

Recessive

C/C-A/C

100 (93.5)

95 (88.8)

1.00

A/A

7 (6.5)

12 (11.2)

1.80 (0.68–4.78)

Overdominant

C/C-A/A

29 (27.1)

41 (38.3)

1.00

A/C

78 (72.9)

66 (61.7)

0.60 (0.34–1.07)

Allele

A

126 (59)

112 (52)

0. 962 (0.656–1.412)

C

88 (41)

102 (48)

IL-13 (−1112C/T)

Codominant

T/T

22 (20.6)

12 (11.2)

1.00

C/T

80 (74.8)

91 (85)

2.09 (0.97–4.48)

C/C

5 (4.7)

4 (3.7)

1.47 (0.33–6.52)

Dominant

T/T

22 (20.6)

12 (11.2)

1.00

C/T-C/C

85 (79.4)

95 (88.8)

2.05 (0.96–4.39)

Recessive

T/T-C/T

102 (95.3)

103 (96.3)

1.00

C/C

5 (4.7)

4 (3.7)

2.05 (0.96–4.39)

Overdominant

T/T-C/C

27 (25.2)

16 (14.9)

1.00

C/T

80 (74.8)

91 (85)

1.92 (0.97–3.82)

Allele

T

124 (58)

115 (54)

1.186 (0.810–1.738)

C

90 (42)

99 (46)

IL-13 (−1512A/C)

Codominant

A/A

23 (21.5)

12 (11.2)

1.00

A/C

80 (74.8)

88 (82.2)

2.11 (0.99–4.51)

C/C

4 (3.7)

7 (6.5)

3.35 (0.82–13.78)

Dominant

A/A

23 (21.5)

12 (11.2)

1.00

A/C-C/C

84 (78.5)

95 (88.8)

2.17 (1.02–4.62)

Recessive

A/A-A/C

103 (96.3)

100 (93.5)

1.00

C/C

4 (3.7)

7 (6.5)

1.80 (0.51–6.35)

Overdominant

A/A-C/C

27 (25.2)

19 (17.8)

1.00

A/C

80 (74.8)

88 (82.2)

1.56 (0.81–3.03)

Allele

A

126 (59)

112 (52)

0.767 (0.523–1.124)

C

88 (42)

102 (48)