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Fig. 2 | BMC Infectious Diseases

Fig. 2

From: Retrospective analysis of acute HBV infections occurred in 1978–79 and 1994–95 in North-East Italy: increasing prevalence of BCP/pre-core mutants in sub-genotype D3

Fig. 2

Genotyping by phylogenetic analysis of S gene sequences from 57 patients. The sequenced region overlapped the Pre-S1, Pre-S2 and S regions of the S open reading frame. The sequence dataset included 19 reference sequences. The phylogenetic tree was constructed by the ML approach with the GTR + G + I substitution model (preliminary estimated to be the best substitution model for the dataset under analysis by the Models tool in MEGA6). Bootstrap values > 70 are reported. A blue circle marks sequences from 1978 to 79, a red circle those from 1994 to 95; reference sequences are shown in bold

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