Table 3 Top 20 pathways by KEGG pathway analysis in 3 cohorts
Rank | Cohort 1 | Cohort 2 | Cohort 3 |
|---|---|---|---|
1 | Chemokine signaling pathway | Chemokine signaling pathway | PI3K-Akt signaling pathway |
2 | Cytokine-cytokine receptor interaction | Cytokine-cytokine receptor interaction | Influenza A |
3 | Focal adhesion | Focal adhesion | Metabolic pathways |
4 | PI3K-Akt signaling pathway | PI3K-Akt signaling pathway | Cytokine-cytokine receptor interaction |
5 | HTLV-I infection | HTLV-I infection | Chemokine signaling pathway |
6 | Metabolic pathways | Metabolic pathways | HTLV-I infection |
7 | ECM-receptor interaction | Cell adhesion molecules (CAMs) | Herpes simplex infection |
8 | Cell adhesion molecules (CAMs) | ECM-receptor interaction | Toxoplasmosis |
9 | p53 signaling pathway | p53 signaling pathway | Hematopoietic cell lineage |
10 | Rheumatoid arthritis | Amoebiasis | Protein processing in endoplasmic reticulum |
11 | Viral carcinogenesis | Proteoglycans in cancer | NF-kappa B signaling pathway |
12 | Amoebiasis | Viral carcinogenesis | Insulin signaling pathway |
13 | Protein digestion and absorption | Rheumatoid arthritis | Leukocyte transendothelial migration |
14 | Proteoglycans in cancer | Influenza A | Focal adhesion |
15 | NF-kappa B signaling pathway | Protein digestion and absorption | Phagosome |
16 | Cell cycle | Hepatitis B | Measles |
17 | Pathways in cancer | NF-kappa B signaling pathway | Adipocytokine signaling pathway |
18 | Toll-like receptor signaling pathway | Fc gamma R-mediated phagocytosis | Antigen processing and presentation |
19 | Influenza A | Cell cycle | Adherens junction |
20 | Hepatitis B | Malaria | Leishmaniasis |