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Table 1 Characteristics, clinical specimen distribution, and culture positive rate of SBA and SAA groups

From: Effect of prior receipt of antibiotics on the pathogen distribution: a retrospective observational cohort study on 27,792 patients

 

SBA group

N = 19,868

SAA group

N = 7924

P value

Demographic

 Age in yr, medians (IQR)

60 (47–70)

61(49–72)

< 0.001

 male (%)

12,477 (62.8%)

4938 (62.3%)

0.443

Department distribution

 Intensive Care Unit

1582 (8.0%)

499 (6.3%)

< 0.001

 Surgery departments

8760 (44.1%)

3873 (48.9%)

< 0.001

 Internal departments

8849 (44.5%)

3114 (39.3%)

< 0.001

 Others

677 (3.4%)

428 (5.5%)

< 0.001

Distribution of Clinical specimens

 Respiratory specimens a

7351 (37.0%)

3162 (39.9%)

< 0.001

 Blood

4229 (21.3%)

1196 (15.1%)

< 0.001

 Body fluid specimens b

1495 (7.5%)

1131 (14.3%)

< 0.001

 Urine

4311 (21.7%)

947 (12.0%)

< 0.001

 Stool

403 (2.0%)

297 (3.7%)

< 0.001

 Other specimens c

2079 (10.5%)

1191 (15.0%)

< 0.001

Culture positive rate

 Culture positive, n (%)

5650 (28.4%)

2014 (25.4%)

< 0.001

 Polymicrobial result, n (%)d

864 (15.3%)

320 (15.9%)

0.525

  1. Abbreviations: SBA specimen taken before antibiotic therapy, SAA specimen taken after antibiotic therapy
  2. a including sputum, throat swab, tracheal aspirate, protected bronchial brush, and bronchoalveolar lavage
  3. b including cerebrospinal fluid, pleural fluid, ascites, bile, puncture fluid, and pericardial effusion
  4. c including intravascular catheter tip, various secretions, peritoneal dialysate, pus, drainage fluid, biopsy tissue and other specimens
  5. d Polymicrobial result was defined as more than one pathogen cultured from the same specimen