The changing epidemiology of hepatitis B and C infections in Nanoro, rural Burkina Faso: a random sampling survey

BMC Infectious Diseases

Table 3 Univariate and multivariate analyses of risk factors of HBsAg sero-positivity, HBV exposure among children participants in rural Nanoro, Burkina Faso, 2018

Child		n	%	Exposure (HBsAg or HBcAb positivity)^a (n = 142)							HBsAb positivity (n = 90)
				Univariate analysis^b				Multivariate analysis^C			Univariate analysis^b				Multivariate analysis ^d
				n(+)	OR	(95%CI)	p	aOR	(95%CI)	p value	n(+)	OR	(95%CI)	p value	aOR	(95%CI)	p value
Age group (years)	[1,2,3,4]	134	55.8	68	1.0		0.003^e	1.0			53	1.0
Age group (years)	[5,6,7,8,9,10]	106	44.2	74	2.2	1.3–3.8		2.1	1.2–3.8	0.008^e	37	0.8	0.5–1.4	0.461
One Penta at least	No	13	5.4	58	1.3	0.4–4.1		–			27	1.0			–	–	–
One Penta at least	Yes	227	94.6	84	1.0		0.451				63	2.1	0.6–7.7	0.279
Completely vaccinated	No	89	37.1	62	2.0	1.2–3.5		1.7	0.9–3.1		29	1.0			–	–	–
Completely vaccinated	Yes	151	62.9	80	1.0		0.012^e	1.0		0.076	61	1.4	0.8–2.4	0.228
Gender	Female	112	46,7	73	1.7	1.0–2.7	0.077	1.7	1.1–2.9		35	1.0			1.0
Gender	Male	128	53.3	69	1.0			1.0		0.047^e	55	1.7	1.0–2.8	0.062	1.6	0.9–2.7	0.104
Birth place	Health center	214	89.2	124	1.0			–			85	1.0			1.0
Birth place	Home birth	26	10.8	18	1.6	0.7–3.9	0.273				5	0.4	0.1–0.9	0.048^e	0.4	0.1–1.1	0.073
Ethnic group	Mossi	224	93.3	131	1.0			–			85	1.0
	Gourounsi	11	4.6	9	3.2	0.7–15.1	0.143				3	0.6	0.2–2.4	0.479	–	–	–
	Other	5	2.1	2	0.5	0.1–2.9	0.418				2	1.1	0.2–6.7	0.925
Blood transfusion	No	228	95.0	135	1.0			–			86	1.0			–
Blood transfusion	Yes	12	5.0	7	1.0	0.3–3.1	0.952				4	1.2	0.4–4.1	0.760		–	–
Birth assistance	Health Skilled	214	89.2	124	1.0			–			85	1.0			–	–	–
	Traditional skilled	12	5.0	10	3.6	0.8–17.0	0.101				2	0.3	0.1–1.4	0.130
	other	14	5.8	8	1.0	0.3–2.9	0.953				3	0.4	0.1–1.5	0.185
Traditional Scarification	No	211	87.9	120	1.0			1.0			81	1.0			–
Traditional Scarification	Yes	29	12.1	22	2.4	1.0–5.8	0.057	2.7	1.1–6.7	0.038^e	9	0.7	0.3–1.7	0.444		–	–

In multivariate analysis, covariates were selected by stepwise procedure (method of increasing and decreasing based on p-value threshold: both of probability to enter and probability to leave are 0.3)
^a hepatitis virus exposure: Seropositivity to hepatitis B surface antigen (HBsAg) or hepatitis B core antibody (HBcAb)
^b χ2– Test or Fisher Exact Test
^c Logistic regression analysis with the stepwise method: R² = 0.0649, model p-value < 0.05, n = 240
^d Logistic regression analysis with the stepwise method: R² = 0.0227, model p-value < 0.03, n = 240
^e Represents statistically significance
OR Odds ratio, aOR adjusted Odds ratio, CI Confident Interval

ISSN: 1471-2334