Table 3 Result summaries for the outcomes measures from 1000 probabilistic simulations for three best calibrations
From: A hybrid simulation model approach to examine bacterial genome sequencing during a hospital outbreak
Total number of: | Optimal Calibration | Calibration #2 | Calibration #3 | ||||||
|---|---|---|---|---|---|---|---|---|---|
Calibrated Real life1 (Scenario 1) | No WGS (Scenario 2) | Early WGS (Scenario 3) | Calibrated Real life1 | No WGS | Early WGS | Calibrated Real life1 | No WGS | Early WGS | |
Colonized patients (SD) | 197 | 352 (170) | 3 (0) | 136 | 219 (90) | 3 (0) | 137 | 448 (320) | 7 (9) |
Detected patients (SD) | 75 | 152 (75) | 1 (0) | 75 | 118 (48) | 1 (0) | 73 | 217 (136) | 4 (7) |
Sequencing tests (SD) | 79 | Â | 2 (0) | 77 | Â | 2 (0) | 74 | Â | 4 (7) |
Bed closures (SD) | 419 | 902 (486) | 11 (2) | 522 | 1145 (489) | 5 (1) | 428 | 1206 (767) | 19 (28) |
Total costs $US (SD) | 318,654 (8406) | 531,109 (234,315) | 45,273 (3155) | 349,160 (8889) | 488,962 (178,224) | 45,637 (2005) | 322,981 (8441) | 705,474 (360,758) | 62,426 (38,507) |
Whole genome sequencing costs | 19,469 (393) | Â | 501 (51) | 18,975 (388) | Â | 493 (10) | 18,221 (385) | Â | 916 (1788) |
Microbiology testing costs | 180,933 (7804) | 292,342 (110,451) | 40,397 (2775) | 193,338 (8169) | 303,916 (104,391) | 42,248 (1996) | 186,432 (7862) | 380,751 (160,304) | 54,187 (28,663) |
Cleaning costs | 27,811 (1346) | 58,075 (31,402) | 733 (205) | 33,125 (1488) | 46,446 (20,638) | 233 (43) | 29,128 (1362) | 78,749 (49,321) | 1406 (1927) |
Nursing costs | 3091 (183) | 6291 (3229) | 44 (8) | 3129 (184) | 4818 (2068) | 43 (2) | 3000 (179) | 8910 (5843) | 157 (302) |
Infection control executive meetings costs | 24,366 (439) | 38,873 (20,044) | 1946 (124) | 22,133 (401) | 29,270 (12,413) | 1925 (34) | 21,803 (391) | 55,779 (35,168) | 2850 (2224) |
Bed closure costs | 62,984 (2481) | 135,528 (72,750) | 1652 (372) | 78,460 (3012) | 104,511 (47,699) | 696 (104) | 64,397 (2523) | 181,286 (115,707) | 2911 (4131) |