Table 1 Characteristics of the included studies
Study | First author | Year | Country | Setting | Age | Study design | HIV% | Culture reference standard | Composite reference standard (CRS) | Total samples (n) | Specimen type |
|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Bholla, M. | 2016 | Tanzania | Primary care Center | 8 week – 16 years | Prospective | 20 | MGIT | Cytology and/or Culture | 75 | Lymph node |
2 | Coetzee, L. | 2014 | South Africa | Tertiary care center | < 13 years | Prospective | 8.3 | MGIT | Cytology and/or Culture | 72 | Lymph node |
3 | Das, A. | 2019 | India | Tertiary care center | 4 month – 14 years | Prospective | 1.75 | MGIT/LJ | Culture | 57 | Lymph node (n = 6), CSF (n = 51), |
4 | Held, M. | 2016 | South Africa | Tertiary care center | < 13 years | Prospective | 10 | MGIT | Culture or histology | 109 | Bone and joint tissue |
5 | Kim, YW. | 2015 | South Korea | Tertiary care center | 0–18 years | Retrospective | 0.8 | MGIT | Culture | 92 | Lymph node (n = 30) CSF (n = 14) Joint fluid (n = 28) Pleural fluid (n = 20) |
6 | Solomons, R.S. | 2015 | South Africa | Tertiary care center | 3 month – 13 years | Prospective | 11 | MGIT | Clinical TBM reference standard | 101 | CSF |
7 | Tortoli, E. | 2012 | Italia | Tertiary care center | 0–18 years | Retrospective | 10 | MGIT/LJ | Histopathology /Improvement on ATT | 132 | Lymph node (n = 89), CSF (n = 43), |
8 | Vadwai | 2011 | South Africa | Tertiary care center | < 13 years | Prospective | 3 | MGIT | Histopathology /Improvement on ATT | 14 | Lymph node (n = 5), CSF(n = 9) |