Table 1 Baseline characteristics by diagnostic group
From: Diagnostic accuracy of the Xpert MTB/Rif Ultra for tuberculosis adenitis
Total (n = 99) | Definite TB (n = 21) | Probable TB (n = 15) | Not TB (n = 63) | P-value | |
|---|---|---|---|---|---|
Sex | |||||
Males | 45 (45%) | 9 (43%) | 4 (27%) | 32 (51%) | 0.233 |
Females | 54 (55%) | 12 (57%) | 11 (73%) | 31 (49%) | |
Age (median [IQR]) | 37 (30–49) | 32 (28–35) | 36 (31–41) | 44 (32–57) | 0.003 |
HIV status | |||||
Positive | 50 (51%) | 13 (62%) | 8 (53%) | 29 (46%) | 0.442 |
Negative | 49 (49%) | 8 (38%) | 7 (47%) | 34 (54%) | |
On ARVS | 31 (62%) | 8 (62%) | 7 (88%) | 16 (55%) | 0.263 |
CD4 count (cells/mm3, median [IQR]) | 216 (82–361) | 100 (55–254) | 351 (88–497) | 252 (92–361) | 0.106 |
< 100 | 16 (32%) | 6 (46%) | 2 (25%) | 8 (28%) | 0.675 |
100–249 | 10 (20%) | 3 (23%) | 1 (13%) | 6 (21%) | |
≥ 250 | 24 (48%) | 4 (31%) | 5 (63%) | 15 (52%) | |
Performance Score | |||||
ECOG 0 | 49 (50%) | 10 (48%) | 9 (60%) | 30 (48%) | 0.979 |
ECOG 1 | 28 (28%) | 6 (29%) | 5 (33%) | 17 (27%) | |
ECOG 2 | 4 (4%) | 1 (5%) | 0 | 3 (5%) | |
ECOG 3 | 16 (16%) | 4 (19%) | 1 (7%) | 11 (17%) | |
ECOG 4 | 2 (2%) | 0 | 0 | 2 (3%) | |
Patient Type | |||||
Inpatient | 16 (16%) | 4 (19%) | 2 (13%) | 10 (16%) | 0.924 |
Outpatient | 83 (84%) | 17 (81%) | 13 (87%) | 53 (84%) | |
Previous tuberculosis | 24 (24%) | 6 (29%) | 6 (40%) | 12 (19%) | 0.205 |
On tuberculosis treatment | 21 (21%) | 6 (29%) | 6 (40%) | 9 (15%) | 0.059 |
Consistency of lymph node | |||||
Firm | 81 (87%) | 16 (80%) | 12 (86%) | 53 (90%) | 0.491 |
Fluctuant | 12 (13%) | 4 (20%) | 2 (14%) | 6 (10%) | |
Symptoms | |||||
Cough | 27 (27%) | 6 (29%) | 3 (20%) | 18 (29%) | 0.79 |
Weight loss | 47 (47%) | 13 (62%) | 5 (33%) | 29 (46%) | 0.222 |
Night sweats | 29 (29%) | 8 (38%) | 3 (20%) | 18 (29%) | 0.49 |
Location of lymph nodes | |||||
Unilateral | 61 (62%) | 13 (62%) | 12 (80%) | 36 (57%) | 0.262 |
Bilateral | 38 (38%) | 8 (38%) | 3 (20%) | 27 (43%) | |
Lymph node FNA/biopsy site | |||||
Neck | 85 (86%) | 19 (90%) | 14 (93%) | 52 (83%) | 0.881 |
Axilla | 10 (10%) | 2 (10%) | 1 (7%) | 7 (11%) | |
Inguinal | 4 (4%) | 0 | 0 | 4 (6%) | |
Blood results (median [IQR]) | |||||
LDH (units/L) | 267 (218–341) | 292 (251–341) | 218 (194–239) | 273 (230–366) | 0.006 |
Hb (g/dL) | 12.1 (9.4–13.4) | 10.5 (8.7–12.1) | 11.8 (9.6–12.7) | 12.4 (9.7–13.5) | 0.041 |
WCC (cells × 10^9) | 6.9 (4.9–9.1) | 5.3 (4.0–8.0) | 5.7 (4.8–7.3) | 7.4 (5.2–9.9) | 0.142 |
Lymphocytes (cells × 10^9) | 1.7 (1.0–2.4) | 1.2 (0.7–1.9) | 1.7 (1.4–2.0) | 1.7 (1.0–2.7) | 0.197 |