Table 3 Diagnostic accuracy of Ultra on FNA and tissue measured against the composite reference standard and culture
From: Diagnostic accuracy of the Xpert MTB/Rif Ultra for tuberculosis adenitis
Sensitivity | Specificity | PPV | NPV | LR+ | LR- | |
|---|---|---|---|---|---|---|
Composite reference standard | ||||||
Ultra on FNA (n = 73 participants) | 21/30; 70% (51–85) | 43/43; 100% (92–100) | 100% | 83% | inv | 0.3 |
Ultra on tissue (n = 81 participants) | 16/24; 67% (45–84) | 55/57; 96% (88–99) | 89% | 87% | 16.8 | 0.3 |
Excluding the 21 participants on tuberculosis therapy>24 h | ||||||
Ultra on FNA (n = 57 participants) | 12/20; 60% (36–81) | 37/37; 100% (91–100) | 100% | 82% | inv | 0.4 |
Ultra on tissue (n = 66 participants) | 10/18; 56% (31–78) | 46/48; 96% (86–99) | 83% | 85% | 14 | 0.5 |
Culture as the reference standard (n = 99 participants) | ||||||
Ultra on FNA (n = 73 participants) | 7/9; 78% (40–97) | 50/64; 78% (66–87) | 33% | 96% | 3.5 | 0.3 |
Ultra on tissue (n = 81 participants) | 9/10; 90% (55–100) | 62/71; 87% (77–94) | 50% | 98% | 6.9 | 0.1 |