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Table 2 Univariate and multivariate logistic regression analyses to show the relationship between characteristics of children hospitalised for malaria and the outcome of interest

From: Malaria in patients with sickle cell anaemia: burden, risk factors and outcome at the Laquintinie hospital, Cameroon

Characteristic

Death, n = 176

Univariate Logistic regression

Multivariate Logistic regression

OR (95% CI)

p-Value

Adj. OR (95% CI)

p-Value

Gender

 Male

74 (42.1%)

1.07 (0.79–1.46)

0,651

1.09 (0.79–1.51)

0.574

 Female

102 (57.9%)

1

 

1

 

Age group

 1-5 years

110 (62.5%)

0.50 (0.17–1.45)

0.122Â¥

Variable not used in multivariate regression

 6-10 years

44 (25.0%)

0.48 (0.17–1.28)

  

 11-15 years

17 (9.7%)

0.38 (0.14–0.98)

  

  > 15 years

5 (2.8%)

1

  

Year of admission

 2018

33 (19.5%)

0.77 (0.49–1.22)

0.503Â¥

Variable not used in multivariate regression

 2017

47 (27.8%)

0.91 (0.60–1.39)

  

 2016

42 (24.9%)

1.10 (0.72–1.69)

  

 2015

47 (27.8%)

1

  

Season of year

 Wet

99 (66.0%)

1.12 (0.79–1.59)

0,512

Variable not used in multivariate regression

 Dry

51 (34.0%)

1

  

Co-Morbidities

 Yes

123 (69.9%)

1.29 (0.93–1.79)

0,132

1.14 (0.81–1.62)

0.446

 No

53 (30.1%)

1

 

1

 

HIV Status

 Positive

1 (0.6%)

0.72 (0.96–5.33)

0,745

1.00 (0.13–7.61)

0.996

 Negative

175 (99.4%

1

 

1

 

Malnutrition

 Yes

2 (1.1%)

0.77 (0.18–3.19)

0,714

1.09 (0.26–4.60)

0.911

 No

174 (98.9%)

1

 

1

 

Readmission(s)*

 Yes

25 (14.2%)

4.08 (2.57–6.49)

<  0.001*

1.33 (0.77–2.29)

0.309

 No

151 (85.8%)

1

 

1

 

Sicke Cell Disease (SCD)*

 Yes

65 (36.9%)

7.69 (5.49–10.78)

<  0.001*

9.18 (6.12–13.78)

<  0.001*

 No

111 (63.1%)

1

 

1

 
  1. ¥ pValue reported following Wald’s test
  2. * statistically significant at p < 0.05
  3. OR is the crude Odd’s ration
  4. Adj. OR is the adjusted Odd’s ratio