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Fig. 10 | BMC Infectious Diseases

Fig. 10

From: Plasmodium yoelii 17XL infection modified maturation and function of dendritic cells by skewing Tregs and amplificating Th17

Fig. 10

Effects of Th17 neutralization on the dynamic of DCs-sectreting-cytokine during P.y17XL infection. Proportion, absolute cell numbers (Column diagram, left) and representative dot plots (right) of DCs-secreting-IL-10 (a, b, c) and DCs-secreting-IL-12 (g, h, i) on CD11c+ DCs were displayed. Flow cytometric analysis was performed on spleen cells from BALB/c mice by double staining with FITC-anti-CD11c, APC-anti-MHC-II, PerCP-anti-CD80 and PE-anti-CD86.Results were presented as the arithmetic mean of 4 mice per group ± SE. Single asterisk (*) and double asterisks (**) indicated P < 0.05 and P < 0.01, respectively, compared with control mice (non-infected mice, 0d). Single pound sign (#) and double pound sign (##) indicates P < 0.05, and P < 0.01, respectively, between infected and Tregs depletion groups mice.* = Calculated value of ‘p’ by student’s t-test; # = Calculated value of ‘p’ by one-way ANON. P-values were calibrated using Bonferroni correction. The data are representative of three separate experiments

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