Fig. 4

Effects of Tregs depletion or Th17 neutralization on the levels of pro- and anti-inflammatory cytokines during P.y17XL infection. a The level of IFN-γ production. b The level of IL-10 production. ELISA was performed on supernatants of cultured spleen cells from BALB/c mice. Results were presented as the arithmetic mean of 4 mice per group ± SE. Single asterisk (*) and double asterisks (**) indicated P < 0.05 and P < 0.01, respectively, compared with control mice (non-infected mice, 0d). Single pound sign (^#) and double pound sign (^##) indicates P < 0.05, and P < 0.01, respectively, between infected and Tregs depletion/Th17 neutralization groups mice. * = Calculated value of ‘p’ by student’s t-test; # = Calculated value of ‘p’ by one-way ANON. P-values were calibrated using Bonferroni correction.The data are representative of three separate experiments