Table 3 Evolving features and outcome of bacterial meningitis in diabetic patients
From: Characteristics and outcome of spontaneous bacterial meningitis in patients with diabetes mellitus
Characteristics | Diabetic Patients (n = 106) | Other Patients (n = 609) | P value |
|---|---|---|---|
Neurological complications | 31 (29.2) | 123 (20.2) | 0.210 |
• Coma | 21 (19.8) | 94 (15.4) | 0.254 |
• Seizures • Focal neurological deficits • Cranial palsies | 18 (17) 8 (7.5) 7 (6.6) | 70 (11.5) 19 (3.1) 28 (4.6) | 0.148 0.046 0.337 |
Systemic complications | 48 (45.3) | 184 (30.2) | 0.024 |
• Acute respiratory failure | 28 (26.4) | 103 (16.9) | 0.029 |
• Acute kidney failure | 27 (25.5) | 72 (11.8) | < 0.001 |
• Septic shock | 19 (17.9) | 88 (14.4) | 0.376 |
• Disseminated intravascular coagulation • Rhabdomyolysis | 11 (10.4) 6 (5.7) | 47 (7.7) 22 (3.6) | 0.677 0.286 |
Therapeutics | |||
• Adequate empiric antibiotic therapy | 93 (87.7) | 568 (93.3) | 0.109 |
• Dexamethasone therapy • Vasoactive drugs • Mechanical ventilation • Dialysis | 39 (36.8) 17 (16) 17 (16) 3 (2.8) | 220 (36.1) 77 (12.6) 88 (14.4) 15 (2.5) | 0.910 0.350 0.839 0.895 |
Outcome | |||
• Neurological sequelae | 8 (7.5) | 19 (3.1) | 0.046 |
• In-hospital mortality | 27 (25.5) | 97 (15.9) | 0.025 |