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Table 4 Factors associated with willingness to take once-daily oral pill as PrEP in the next six months (among GBMSM with experience of SDU in the past year and were not on PrEP, n = 70)

From: Uptake and willingness to use PrEP among Chinese gay, bisexual and other men who have sex with men with experience of sexualized drug use in the past year

 

OR (95%CI)

AOR (95%CI)

Patterns of SDU

 Poly-use of psychoactive substances during SDU the past year

  No

1.0

 

  Yes

2.02 (0.58, 7.01)

–

 Time since the first episode of SDU

   < 1 year

1.0

 

  1–2 years

1.00 (0.21, 4.77)

 

  3–5 years

1.14 (0.25, 5.33)

 

   > 5 years

0.59 (0.18, 1.96)

–

Frequency of SDU in the past year

 1 episode/month

1.0

 

 1–2 episodes/month

0.81 (0.25, 2.67)

 

  ≥ 3 episodes/month

1.33 (0.39, 4.58)

–

Condomless anal intercourse in the past year

 No

1.0

 

 Yes

0.88 (0.32, 2.40)

–

Perceptions related to PrEP

 Positive Attitude Scale

2.30 (1.46, 3.62)***

2.37 (1.47, 3.82)***

 Negative Attitude Scale

1.16 (0.91, 1.47)

–

 People who are important to you will support you to use PrEP

  Disagree/neutral

1.0

1.0

  Agree

9.14 (2.90, 28.77)***

9.67 (2.95, 31.71)***

In general, you are confident in taking PrEP every day in the next six months

 Strongly disagree/disagree/neutral

1.0

1.0

 Agree/strongly agree

20.57 (5.75, 73.65)***

19.68 (5.44, 71.26)***

Mental health status

 Depressive symptoms

  No clinical depressive symptoms

1.0

 

  Presence of clinical depressive symptoms

0.88 (0.32, 2.40)

–

 Anxiety

  No/mild/anxiety

1.0

 

  Severe anxiety

0.46 (0.08, 2.45)

–

  1. OR: crude odds ratios
  2. AOR: multivariate odds ratios obtained by multivariate logistic regression using variables in Tables 3 and 4 that were found to be statistically significant in the univariate analysis as candidates
  3. 95%CI 95% confidence interval
  4. OR, AOR and 95% were bold for variables with p < 0.05
  5. *** P < 0.001, −--: not considered in the model