Genes | Haplotype | Codona | Number (%) |
---|---|---|---|
Pvdhfr | |||
Wild type | I13F57S58T61H99S117I173 | 3 (5.17) | |
Mutant type | 55 (94.83) | ||
Mutant tandem repeat | I13F57S58T61-S117I173 | 10 (17.24) | |
Single mutant | I13F57S58T61S99S117I173 | 17 (29.31) | |
Double mutant and tandem repeat | I13F57R58T61-N117I173 | 12 (20.69) | |
Quadruple mutant(a) | I13I57R58M61H99T117I173 | 9 (15.52) | |
Quadruple mutant(b) | I13L57R58M61H99T117I173 | 5 (8.62) | |
Quintuple mutant | I13I57R58M61S99T117I173 | 2 (3.45) | |
Pvdhps | |||
Wild type | S382A383K512A553R580V585 | 29 (50.00) | |
Single mutant | S382G383K512A553R580V585 | 20 (34.48) | |
Double mutant | S382G383K512G553R580V585 | 8 (13.79) | |
Quadruple mutant | C382G383E512G553R580V585 | 1 (1.72) | |
Pvmdr1 | |||
Wild type | T958Y976K997F1076 | 0 | |
Single mutant | M958Y976K997F1076 | 9 (15.52) | |
Double mutant | M958Y976K997L1076 | 49 (84.48) | |
Pvcrt-o | |||
Wild type | 47 (81.03) | ||
Mutant (“AAG” insertion) | 11 (18.97) |