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Table 3 Prevalence of haplotypes of Pvcrt-o, Pvmdr1, Pvdhps and Pvdhfr in P. vivax isolates

From: Prevalence of molecular markers associated with drug resistance of Plasmodium vivax isolates in Western Yunnan Province, China

GenesHaplotypeCodonaNumber (%)
Pvdhfr
 Wild typeI13F57S58T61H99S117I1733 (5.17)
 Mutant type 55 (94.83)
 Mutant tandem repeatI13F57S58T61-S117I17310 (17.24)
 Single mutantI13F57S58T61S99S117I17317 (29.31)
 Double mutant and tandem repeatI13F57R58T61-N117I17312 (20.69)
 Quadruple mutant(a)I13I57R58M61H99T117I1739 (15.52)
 Quadruple mutant(b)I13L57R58M61H99T117I1735 (8.62)
 Quintuple mutantI13I57R58M61S99T117I1732 (3.45)
Pvdhps
 Wild typeS382A383K512A553R580V58529 (50.00)
 Single mutantS382G383K512A553R580V58520 (34.48)
 Double mutantS382G383K512G553R580V5858 (13.79)
 Quadruple mutantC382G383E512G553R580V5851 (1.72)
Pvmdr1
 Wild typeT958Y976K997F10760
 Single mutantM958Y976K997F10769 (15.52)
 Double mutantM958Y976K997L107649 (84.48)
Pvcrt-o
 Wild type 47 (81.03)
 Mutant (“AAG” insertion) 11 (18.97)
  1. a:Mutant amino acids are shown in bold