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Table 3 Association between patient characteristics and days of well response

From: Prevalence and risk factors related to poor outcome of patients with severe Plasmodium vivax infection: a systematic review, meta-analysis, and analysis of case reports

Patient Characteristics

Days of well response

P-value*

Odd’s ratio (95%CI)

≥ 7 days

< 7 days

Impaired consciousness

 - Yes

7 (17.1)

13 (59.1)

0.001

0.14 (0.04–0.46)

 - No

34 (82.9)

9 (40.9)

  

Convulsion

 - Yes

0

8 (4.5)

< 0.0001

3.93 (2.15–6.18)

 - No

41 (100)

14 (99.5)

  

ARDS

 - Yes

19 (46.3)

3 (13.6)

0.009

5.47 (1.5–21.39)

 - No

22 (53.7)

19 (86.4)

  

Renal failure

 - Yes

17 (41.5)

2 (9.1)

0.008

7.08 (1.46–34.4)

 - No

24 (58.5)

20 (90.9)

  

Jaundice

 - Yes

12 (29.3)

1 (4.5)

0.021

8.69 (1.05–72.1)

 - No

29 (70.7)

21 (95.5)

  

Urine (anuria/oliguria)

 - Yes

12 (29.3)

1 (4.5)

0.021

8.69 (1.05–72.1)

 - No

29 (70.7)

21 (95.5)

  

Splenomegaly

 - Yes

9 (22)

12 (54.5)

0.009

0.23 (0.08–0.72)

 - No

32 (78)

10 (45.5)

  

Complications during treatment

 - Yes

25 (61)

7 (31.8)

0.027

3.35 (1.12–10)

 - No

16 (39)

15 (68.2)

  
 

Required 2ndantimalarial drugs

 

Yes

No

Complications during treatment

 - Yes

11 (84.6)

23 (36.5)

0.001

9.57 (1.95–46.98)

 - No

2 (15.4)

40 (63.5)

  
  1. *Pearson Chi-Square